Find and compare 5 Star hotels in Medical Center District

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Featured Medical Center District 5 Star hotels

Thompson San Antonio - Riverwalk, by Hyatt

115 Lexington Avenue, San Antonio, TX

Free cancellation

CA $354

per night

May 12 - May 13

Enjoy free WiFi, a full-service spa, and breakfast (surcharge).

Pet-friendly

Spa

The Luxury Suites at Arrive Eilan

17803 La Cantera Terrace, San Antonio, TX

Get rates

Stay at this 5-star luxury apartment in San Antonio. Enjoy free WiFi, free parking, and balconies or patios. Popular attractions Six Flags Fiesta Texas and The Rim Shopping Center are located nearby.

Pool

Parking included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medical Center District hotels essential information

Accommodation	4,352 hotels
Lowest Price	CA $354
Highest Price	CA $354
Popular hotels	Thompson San Antonio - Riverwalk, by Hyatt, The Luxury Suites at Arrive Eilan