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Featured Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $170 per night from May 23 to May 24
CA $170
CA $170 total
May 23 - May 24
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,005 reviews)
El hotel está en una excelente ubicación a metros del mall Cenco costanera . La habitación muy buen tamaño . El desayuno muy bueno y completo.todo buenísimo , lo único que no estuvimos muy conformes es que la piscina no está a buena temperatura, bastante fría , imposible meterse en esta época ( otoño) ...

Reviewed on May 3, 2026

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $301 per night from May 22 to May 23
CA $301
CA $301 total
May 22 - May 23
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,001 reviews)
Great hotel. The staff was amazing and they were very friendly, nice and welcoming to my whole family. Very good location.

Reviewed on May 4, 2026

Opens in a new windowMandarin Oriental, Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $355 per night from May 22 to May 23
CA $355
CA $355 total
May 22 - May 23
Book a stay at this luxury hotel in Santiago. Enjoy a rooftop terrace, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in ...
9.4/10 Exceptional! (621 reviews)
One of the new vest hotels I have ever stayed at. The amenities were fabulous, like cation is great. Staff was above and beyond, so friendly and helpful, phenomenal!! I would choose this hotel in Santiago and very time I visit.

Reviewed on May 13, 2026

Opens in a new windowThe Ritz-Carlton, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $245 per night from May 29 to May 30
CA $245
CA $245 total
May 29 - May 30
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (543 reviews)
Excellent bar

Reviewed on Apr 23, 2026

Opens in a new windowW Santiago
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $370 per night from May 15 to May 16
CA $370
CA $370 total
May 15 - May 16
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.6/10 Exceptional! (716 reviews)
Beautiful hotel, lovely rooms, excellent bar and restaurant on rooftop. Staff was amazing.

Reviewed on May 13, 2026

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $129 per night from May 30 to May 31
CA $129
CA $129 total
May 30 - May 31
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
9/10 Wonderful! (947 reviews)
The Team , from senior management plus all at the front desk ,during my stay, were great. They showed compassion and gave their time and energy to help the customer. This was not just when I arrived but during my 3 day stay. Great Team again many thanks to all and see you soon.

Reviewed on Apr 26, 2026

Opens in a new windowPullman Santiago Vitacura
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $240 per night from May 17 to May 18
CA $240
CA $240 total
May 17 - May 18
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Arauco Mall and Costanera Center ...
8.6/10 Excellent! (581 reviews)
It looks way more luxurious online than in person, the gym, the spa were so disappointing.

Reviewed on Apr 28, 2026

Opens in a new windowNoi Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Parque Arauco Mall and Costanera Center ...
10/10 Exceptional! (4 reviews)
Newly renovated, modern super clean and all the amenities

Reviewed on Apr 26, 2026

Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers