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Featured Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $185 per night from Jan 22 to Jan 23
CA $185
CA $185 total
Jan 22 - Jan 23
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,002 reviews)
Todo muy bien, la unica molestia es que las llaves de la habitación se desprograma siempre

Reviewed on Dec 25, 2025

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundable
The price is CA $348 per night from Jan 10 to Jan 11
CA $348
CA $348 total
Jan 10 - Jan 11
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (940 reviews)
Excellent Stay and the staff is attentive and friendly. Thank you!

Reviewed on Dec 28, 2025

Opens in a new windowMandarin Oriental, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $349 per night from Jan 17 to Jan 18
CA $349
CA $349 total
Jan 17 - Jan 18
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (514 reviews)
Excellent hotel

Reviewed on Sep 7, 2025

Opens in a new windowW Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $424 per night from Jan 10 to Jan 11
CA $424
CA $424 total
Jan 10 - Jan 11
Book a stay at this luxury hotel in Santiago. Enjoy 24-hour room service, a health club, and WiFi (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (592 reviews)
Good hotel in Santiago,clean and staff were friendly.

Reviewed on Nov 23, 2025

Opens in a new windowThe Ritz-Carlton, Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $268 per night from Jan 4 to Jan 5
CA $268
CA $268 total
Jan 4 - Jan 5
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Costanera Center and Parque Arauco Mall ...
8.6/10 Excellent! (552 reviews)
The gym was terrible. Other than that it was great.

Reviewed on Nov 22, 2025

Opens in a new windowNoi Vitacura
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $528 per night from Jan 10 to Jan 11
CA $528
CA $528 total
Jan 10 - Jan 11
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.4/10 Exceptional! (681 reviews)
This was a 10/10 stay!! The hotel is beautiful and the staff are SO friendly and attentive. The rooms are so nice and the rooftop pool/restaurant is beautiful. some of the best service I’ve received.

Reviewed on Dec 13, 2025

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $148 per night from Jan 17 to Jan 18
CA $148
CA $148 total
Jan 17 - Jan 18
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
8.8/10 Excellent! (910 reviews)
Clean rooms.Good hotel staff

Reviewed on Dec 22, 2025

Opens in a new windowPullman Santiago Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Costanera Center and Parque Arauco ...
10/10 Exceptional! (1 review)
Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers