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Featured Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $171 per night from Dec 21 to Dec 22
CA $171
CA $171 total
Dec 21 - Dec 22
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,002 reviews)
Nice hotel.

Reviewed on Dec 6, 2025

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $397 per night from Dec 27 to Dec 28
CA $397
CA $397 total
Dec 27 - Dec 28
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (934 reviews)
Great staff in a wonderful hotel.

Reviewed on Dec 10, 2025

Opens in a new windowMandarin Oriental, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $408 per night from Jan 10 to Jan 11
CA $408
CA $408 total
Jan 10 - Jan 11, 2026
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (513 reviews)
Excellent hotel

Reviewed on Sep 7, 2025

Opens in a new windowW Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $426 per night from Jan 10 to Jan 11
CA $426
CA $426 total
Jan 10 - Jan 11, 2026
Book a stay at this luxury hotel in Santiago. Enjoy 24-hour room service, a health club, and WiFi (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (590 reviews)
Good hotel in Santiago,clean and staff were friendly.

Reviewed on Nov 23, 2025

Opens in a new windowThe Ritz-Carlton, Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $269 per night from Dec 28 to Dec 29
CA $269
CA $269 total
Dec 28 - Dec 29
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Costanera Center and Parque Arauco Mall ...
8.6/10 Excellent! (546 reviews)
The gym was terrible. Other than that it was great.

Reviewed on Nov 22, 2025

Opens in a new windowNoi Vitacura
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $324 per night from Dec 24 to Dec 25
CA $324
CA $324 total
Dec 24 - Dec 25
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.4/10 Exceptional! (675 reviews)
All of the above

Reviewed on Dec 8, 2025

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Jan 11 to Jan 12
CA $134
CA $134 total
Jan 11 - Jan 12, 2026
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
8.8/10 Excellent! (907 reviews)
Clean and quiet

Reviewed on Oct 9, 2025

Opens in a new windowPullman Santiago Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Costanera Center and Parque Arauco ...
Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers