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Featured Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $188 per night from Jan 22 to Jan 23
CA $188
CA $188 total
Jan 22 - Jan 23
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,006 reviews)
Great location, kind staff, I wish a few spoke a bit more Spanish. I do think the breakfast could have been a lot better. Again, the location is perfect!!!

Reviewed on Jan 1, 2026

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundable
The price is CA $409 per night from Jan 17 to Jan 18
CA $409
CA $409 total
Jan 17 - Jan 18
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (946 reviews)
Very good

Reviewed on Jan 1, 2026

Opens in a new windowMandarin Oriental, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $359 per night from Jan 17 to Jan 18
CA $359
CA $359 total
Jan 17 - Jan 18
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (518 reviews)
Excellent hotel

Reviewed on Sep 7, 2025

Opens in a new windowW Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $427 per night from Jan 10 to Jan 11
CA $427
CA $427 total
Jan 10 - Jan 11
Book a stay at this luxury hotel in Santiago. Enjoy 24-hour room service, a health club, and WiFi (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (592 reviews)
Good hotel in Santiago,clean and staff were friendly.

Reviewed on Nov 23, 2025

Opens in a new windowThe Ritz-Carlton, Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $255 per night from Jan 8 to Jan 9
CA $255
CA $255 total
Jan 8 - Jan 9
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Costanera Center and Parque Arauco Mall ...
8.6/10 Excellent! (554 reviews)
The gym was terrible. Other than that it was great.

Reviewed on Nov 22, 2025

Opens in a new windowNoi Vitacura
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $530 per night from Feb 7 to Feb 8
CA $530
CA $530 total
Feb 7 - Feb 8
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.4/10 Exceptional! (684 reviews)
Staff. Great size of the room

Reviewed on Jan 2, 2026

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $149 per night from Feb 7 to Feb 8
CA $149
CA $149 total
Feb 7 - Feb 8
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
8.8/10 Excellent! (911 reviews)
Was a vg room, lot of space, excellent view, very polite helpful staff

Reviewed on Dec 31, 2025

Opens in a new windowPullman Santiago Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Costanera Center and Parque Arauco ...
10/10 Exceptional! (1 review)
Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers