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Featured Santiago 5 Star hotels

Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $311 per night from Jun 27 to Jun 28
CA $311
CA $311 total
Jun 27 - Jun 28
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,003 reviews)
"Increíble hotel, hermosas habitaciones y una vista panoramica de Santiago espectacular. El Staff muy amable y la habitación impecable"

Reviewed on Jun 20, 2026

Opens in a new windowMandarin Oriental, Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $367 per night from Jun 26 to Jun 27
CA $367
CA $367 total
Jun 26 - Jun 27
Book a stay at this luxury hotel in Santiago. Enjoy a rooftop terrace, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in ...
9.4/10 Exceptional! (632 reviews)
"Couldn’t fault the hotel. They were very accommodating and the staff everywhere were incredible, Patricia in the restaurant was fabulous and really helpful. Great location. Very spacious room."

Reviewed on Jun 11, 2026

Opens in a new windowThe Ritz-Carlton, Santiago
NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from Jun 27 to Jun 28
CA $176
CA $176 total
Jun 27 - Jun 28
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
"I would stay here again. - easy self park - nice breakfast - dinner and service was very good - very close to shopping mall"

Reviewed on Jun 17, 2026

Opens in a new windowNH Collection Plaza Santiago
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $263 per night from Jul 16 to Jul 17
CA $263
CA $263 total
Jul 16 - Jul 17
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.6/10 Exceptional! (727 reviews)
"very good and nice hotel..."

Reviewed on Jun 17, 2026

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $134 per night from Jun 21 to Jun 22
CA $134
CA $134 total
Jun 21 - Jun 22
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
9/10 Wonderful! (957 reviews)
"Me sentí muy cómoda en todo el tiempo de mi estancia, el personal fue muy amable, me sentí genial. Lo recomiendo"

Reviewed on Jun 4, 2026

Opens in a new windowPullman Santiago Vitacura
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $248 per night from Jun 26 to Jun 27
CA $248
CA $248 total
Jun 26 - Jun 27
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (550 reviews)
"All fine !!"

Reviewed on Jun 15, 2026

Opens in a new windowW Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $249 per night from Jun 25 to Jun 26
CA $249
CA $249 total
Jun 25 - Jun 26
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Arauco Mall and Costanera Center ...
Opens in a new windowNoi Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Parque Arauco Mall and Costanera Center ...
10/10 Exceptional! (4 reviews)
"Newly renovated, modern super clean and all the amenities"

Reviewed on Apr 26, 2026

Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers