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Featured Santiago 5 Star hotels

Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $324 per night from Dec 4 to Dec 5
CA $324
CA $324 total
Dec 4 - Dec 5
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.4/10 Exceptional! (1,003 reviews)
"Nice stay lovely room excellent housekeeping. Knocked a bit off as service in the Italian restaurant and at breakfast was a bit hit and miss. Long waits and food not appearing in time if at all."

Reviewed on Nov 7, 2026

Opens in a new windowMandarin Oriental, Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $451 per night from Nov 13 to Nov 14
CA $451
CA $451 total
Nov 13 - Nov 14
Book a stay at this luxury hotel in Santiago. Enjoy a rooftop terrace, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in ...
9.4/10 Exceptional! (679 reviews)
"Execelente ubicación"

Reviewed on Nov 7, 2026

Opens in a new windowThe Ritz-Carlton, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $329 per night from Dec 6 to Dec 7
CA $329
CA $329 total
Dec 6 - Dec 7
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (599 reviews)
"Outstanding hotel in a perfect location. Walking distance to numerous bars and restaurants. Easy access to the metro and transportation. Staff was incredibly helpful and kind."

Reviewed on Nov 2, 2026

Opens in a new windowW Santiago
NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Dec 4 to Dec 5
CA $139
CA $139 total
Dec 4 - Dec 5
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowNH Collection Plaza Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $207 per night from Dec 6 to Dec 7
CA $207
CA $207 total
Dec 6 - Dec 7
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Arauco Mall and Costanera Center ...
Opens in a new windowNoi Vitacura
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $346 per night from Nov 17 to Nov 18
CA $346
CA $346 total
Nov 17 - Nov 18
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.6/10 Exceptional! (792 reviews)
"Loved the hotel. The staff were so friendly and welcoming. The bed was huge and comfortable. The breakfast could have been better but it didn’t take away from an overall five star experience!"

Reviewed on Nov 6, 2026

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $159 per night from Dec 4 to Dec 5
CA $159
CA $159 total
Dec 4 - Dec 5
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
Opens in a new windowPullman Santiago Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Parque Arauco Mall and Costanera Center ...
9.8/10 Exceptional! (6 reviews)
"Newly renovated, modern super clean and all the amenities"

Reviewed on Apr 26, 2026

Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers