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Featured Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $186 per night from Jul 31 to Aug 1
CA $186
CA $186 total
Jul 31 - Aug 1
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (1,003 reviews)
"La propiedad esta en una buena zona, cerca del costanera center pero la atención es muy mala,,la recepción nada amable, en la habitación 510 el baño tenía moho, la señora que limpia en los 6 días nunca limpió la habitación, solamente arreglaba la cama. Nosotros regularmente nos quedamos en los NH ..."

Reviewed on Jul 4, 2026

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $294 per night from Aug 1 to Aug 2
CA $294
CA $294 total
Aug 1 - Aug 2
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (1,002 reviews)
"The staff Was Very friendly the hotel was well. Location rooms were big and comfortable. The front desk and the restaurant. Staff was amazing. The food really very excellent."

Reviewed on Jun 30, 2026

Opens in a new windowMandarin Oriental, Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $368 per night from Jul 10 to Jul 11
CA $368
CA $368 total
Jul 10 - Jul 11
Book a stay at this luxury hotel in Santiago. Enjoy a rooftop terrace, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in ...
9.4/10 Exceptional! (638 reviews)
"Couldn’t fault the hotel. They were very accommodating and the staff everywhere were incredible, Patricia in the restaurant was fabulous and really helpful. Great location. Very spacious room."

Reviewed on Jun 11, 2026

Opens in a new windowThe Ritz-Carlton, Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from Aug 1 to Aug 2
CA $139
CA $139 total
Aug 1 - Aug 2
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
9/10 Wonderful! (962 reviews)
"Great modern hotel the restaurant is very good, the service excellent, I recommend this for a short stay anytime. Location is great too, near main avenue with easy transpottation"

Reviewed on Jul 3, 2026

Opens in a new windowPullman Santiago Vitacura
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $249 per night from Jul 11 to Jul 12
CA $249
CA $249 total
Jul 11 - Jul 12
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (551 reviews)
"Excelente"

Reviewed on Jul 3, 2026

Opens in a new windowW Santiago
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $334 per night from Jul 6 to Jul 7
CA $334
CA $334 total
Jul 6 - Jul 7
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.6/10 Exceptional! (737 reviews)
"This is a jewel hotel. The staff is awesome and specially Gabriela at the restaurant and the front desk. The attention to all details is special."

Reviewed on Jun 30, 2026

Opens in a new windowThe Singular Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $189 per night from Aug 1 to Aug 2
CA $189
CA $189 total
Aug 1 - Aug 2
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Parque Arauco Mall and Costanera Center ...
Opens in a new windowNoi Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Parque Arauco Mall and Costanera Center ...
9.8/10 Exceptional! (6 reviews)
"Newly renovated, modern super clean and all the amenities"

Reviewed on Apr 26, 2026

Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers