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Featured Santiago 5 Star hotels

NH Collection Plaza Santiago

NH Collection Plaza Santiago

5 out of 5
Avenida Vitacura 2610 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $280 per night from Mar 9 to Mar 10
CA $280
CA $280 total
Mar 9 - Mar 10
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,001 reviews)
Yes.

Reviewed on Feb 4, 2026

Opens in a new windowNH Collection Plaza Santiago
Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Kennedy Avenue #4601 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $454 per night from Feb 12 to Feb 13
CA $454
CA $454 total
Feb 12 - Feb 13
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the helpful staff and the property condition ...
9.2/10 Wonderful! (963 reviews)
Our room was clean and beautifully presented. Contrary to other reviews we found the staff to be extremely helpful and supportive. We would stay here again without hesitation.

Reviewed on Jan 26, 2026

Opens in a new windowMandarin Oriental, Santiago
W Santiago

W Santiago

5 out of 5
Isidora Goyenechea 3000 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $349 per night from Feb 13 to Feb 14
CA $349
CA $349 total
Feb 13 - Feb 14
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (526 reviews)
New Year’s Eve has a good rooftop party

Reviewed on Jan 14, 2026

Opens in a new windowW Santiago
The Ritz-Carlton, Santiago

The Ritz-Carlton, Santiago

5 out of 5
Calle El Alcalde 15 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $492 per night from Feb 12 to Feb 13
CA $492
CA $492 total
Feb 12 - Feb 13
Book a stay at this luxury hotel in Santiago. Enjoy 24-hour room service, a health club, and WiFi (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (598 reviews)
A wonderful hotel!!

Reviewed on Jan 21, 2026

Opens in a new windowThe Ritz-Carlton, Santiago
Noi Vitacura

Noi Vitacura

5 out of 5
Av. Nueva Costanera 3736 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $256 per night from Feb 23 to Feb 24
CA $256
CA $256 total
Feb 23 - Feb 24
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Costanera Center and Parque Arauco Mall ...
8.6/10 Excellent! (562 reviews)
The rooms are very clean, although did smell like someone had smoked there before. Overall great Hotel, rooms are large and very comfortable. Would stay there again

Reviewed on Feb 4, 2026

Opens in a new windowNoi Vitacura
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $528 per night from Feb 7 to Feb 8
CA $528
CA $528 total
Feb 7 - Feb 8
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.4/10 Exceptional! (694 reviews)
Great hotel. Great experience.

Reviewed on Jan 30, 2026

Opens in a new windowThe Singular Santiago
Pullman Santiago Vitacura

Pullman Santiago Vitacura

5 out of 5
Av. Vitacura 3201 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is CA $148 per night from Feb 21 to Feb 22
CA $148
CA $148 total
Feb 21 - Feb 22
Book a stay at this luxury hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
8.8/10 Excellent! (923 reviews)
Was a vg room, lot of space, excellent view, very polite helpful staff

Reviewed on Dec 31, 2025

Opens in a new windowPullman Santiago Vitacura
LUUM by Norus

LUUM by Norus

5 out of 5
Rep Árabe de Egipto 670 Santiago Santiago
Book a stay at this luxury apartment in Santiago. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Costanera Center and Parque Arauco ...
10/10 Exceptional! (3 reviews)
Opens in a new windowLUUM by Norus
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Five Star Hotels in Santiago

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Santiago to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Santiago 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Santiago before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Santiago hotel reviews by fellow wanderers