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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Enjoy the free WiFi at this hotel

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

In-room safe, desk, laptop workspace, blackout drapes
Business centre
Lobby sitting area
Lobby sitting area
Free daily buffet breakfast

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪6 min walk‬
  • Place, Niagara Square
    ‪8 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

Standard Room

Standard Room

9.2 out of 10
Wonderful
(26 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom

Suite, 1 Bedroom

8.8 out of 10
Excellent
(51 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

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About the area

Buffalo

What's nearby

  • Chippewa District - 1 min walk - 0.0 km
  • Market Arcade Building - 1 min walk - 0.1 km
  • Shea's Performing Arts Center - 2 min walk - 0.2 km
  • Buffalo Niagara Convention Center - 6 min walk - 0.6 km
  • Niagara Square - 8 min walk - 0.7 km

Restaurants

  • ‪Big Ditch Brewing Company - ‬4 min walk
  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Bada Bing - ‬2 min walk
  • ‪Eddie Brady's - ‬3 min walk
  • ‪Lucky Day Whiskey Bar - ‬4 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Enjoy the free WiFi at this hotel
Public spaces have free WiFi. You'll find a business center on site. Free breakfast is available daily.

This hotel is smoke free.

  • Buffet breakfast (free)
  • Business facilities
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Elevator
  • No smoking on site
Accommodations have separate sitting areas and include sofa beds and desks. Cable television is provided. Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include safes and phones; free local calls are provided (restrictions may apply). Refrigerators, microwaves, and coffee/tea makers are provided. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers. Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Cribs/infant beds (complimentary) are also available. Housekeeping is provided daily.

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includes taxes & fees
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Property amenities

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

Room amenities

Entertainment

  • 49-inch TV with cable channels

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Contactless check-in available

Check-out

Contactless check-out available

Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. This property uses eco-friendly cleaning products.
    For guests' safety, the property includes a fire extinguisher, a smoke detector, and window guards in each accommodation.

We should mention

  • Children stay free in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel

Comfort Suites Hotel Downtown

Comfort Suites Downtown Hotel Buffalo

Comfort Suites Downtown Buffalo

Comfort Suites Downtown Buffalo Hotel

Comfort Suites Buffalo

Buffalo Comfort Suites

Holiday Inn Express Buffalo Downtown

Holiday Inn Express Suites Buffalo Downtown

Holiday Inn Express Suites Buffalo Downtown Medical CTR

Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Breakfast is available for a fee.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of May 13, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on May 31, 2026 start from CA $179, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

No, there is no casino at this hotel.

Free parking is not available at this hotel.

There are no spa services available at this hotel.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 568 out of 1011 reviews
Rating 8 - Good. 275 out of 1011 reviews
Rating 6 - Okay. 74 out of 1011 reviews
Rating 4 - Poor. 41 out of 1011 reviews
Rating 2 - Terrible. 53 out of 1011 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

8/10 Good

Ryan

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Was a very nice place, the bed was comfortable and it was great to have a separate area from the bed that also had a tv. There is no parking at the hotel itself. On the weekend one of the streets has free parking if you can find a spot. As for the weekdays you would have to park in a parking garage.
Stayed 1 night in Apr 2026

8/10 Good

hector

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Stayed 1 night in Feb 2026

2/10 Terrible

Grace

Stayed 1 night in Jan 2026

8/10 Good

Catherine

Liked: Amenities, property conditions & facilities
Staff
Stayed 1 night in Feb 2026

6/10 Okay

Lee

Liked: Staff & service
Staff very good. Hotel quite worn in parts; i.e getting random electric shocks from door handles and light switches. Food smell in room everytime fans active (food hall next door). Beds comfy and plenty of space in room/suite. Complimentary breakfast okay with fairly small choice. A fair price for what we paid considering nearby alternatives were more expensive and we were located near numerous bars and restaurants.
Stayed 4 nights in Feb 2026

6/10 Okay

Amber

Stayed 2 nights in Feb 2026

10/10 Excellent

NaDav-ya

Stayed 1 night in Feb 2026

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026

10/10 Excellent

Julie

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room clean most comfortable bed I have ever slept in!
Stayed 1 night in Jan 2026

2/10 Terrible

MASAHIRO

Business traveller
Liked: Cleanliness, amenities, property conditions & facilities
When I checked out, I paid for my stay with a credit card at the front desk, but requested a receipt, which was refused. I was on a business trip, but without a receipt, I cannot settle the expenses. The hotel must immediately send me a receipt by email. If they refuse, I will not hesitate to sue them.
Stayed 3 nights in Feb 2026

4/10 Poor

Justin

Travelled with partner
Room was dark. Fire alarm went off at 5 am.
Stayed 1 night in Feb 2026

4/10 Poor

Robert

Travelled with family, Travelled with partner
Disliked: Cleanliness, amenities, property conditions & facilities
Upon arrival the first room Ingotnto had not been cleaned or serviced. When I notified the front deak she told me thats why she doesnt like checking people in early with a clear attititude. The overall appearance and cleanliness of the hotel was sub par, even by holiday inn express standards.
Stayed 1 night in Jan 2026

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026

2/10 Terrible

Stephanie

Disliked: Cleanliness, amenities, property conditions & facilities
Very disappointing stay. At check-in, the front desk agent was distracted and unprofessional, carrying on another conversation while helping me. The room keys didn’t work, and I had to go back and forth to the front desk multiple times, waiting in long lines each time. It took about 45 minutes just to get into my room, which made me late when I already had somewhere to be. Once inside, the room clearly wasn’t properly cleaned—there were other guests’ hair products on the floor, a hole in the door, and the toilet wouldn’t flush unless you tried several times. Overall, one of the worst hotel experiences I’ve had. Would not recommend.
Stayed 1 night in Jan 2026

4/10 Poor

Kaylee

Travelled with partner
Liked: Cleanliness
Disliked: Amenities, property conditions & facilities
Check in was terrible, keys didn’t work, staff barely batted an eye at me, rude staff, wifi was terrible, no option for early check in, parking too far away
Stayed 1 night in Jan 2026

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026

8/10 Good

Jennifer

Stayed 1 night in Nov 2025

10/10 Excellent

Richard

Stayed 1 night in Feb 2026

10/10 Excellent

Bryan

Stayed 1 night in Jan 2026

10/10 Excellent

Charles

Liked: Cleanliness, property conditions & facilities
No parking is not a good thing
Stayed 1 night in Jan 2026

10/10 Excellent

Mallory

Travelled with partner
Liked: Cleanliness, property conditions & facilities
The room was great and spacious
Stayed 1 night in Jan 2026

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026

2/10 Terrible

William

Disliked: Cleanliness, staff & service, amenities
This has got to be the worst place I've ever stayed in , rude staff and no help what's o ever , I will never stay here again let alone a holiday in in the near future .. dirty room and parking is 2 blocks away
Stayed 1 night in Jan 2026

10/10 Excellent

Camryn

Stayed 1 night in Jan 2026

10/10 Excellent

Shauna

Stayed 1 night in Jan 2026