Book a hotel near Mississippi River, United States of America
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Hotels near Mississippi River

Hampton Inn St. Charles St. Peters
3720 W Clay St St. Charles MO
Free cancellation
Reserve now, pay when you stay
98.48 km from Mississippi River
The price is CA $122 per night
CA $122
CA $140 total
Dec 14 - Dec 15
includes taxes & fees
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Ameristar Casino St. Charles and Cave Spring Golf Center are located nearby.
Pool
Hot tub

Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Free cancellation
Reserve now, pay when you stay
104.14 km from Mississippi River
Book a stay at this luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 6 restaurants. Our guests praise the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Lewis & Clark Boathouse and Nature Center are located nearby.
Pool
Hot tub

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free cancellation
Reserve now, pay when you stay
105.73 km from Mississippi River
The price is CA $108 per night
CA $108
CA $146 total
Dec 15 - Dec 16
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free parking, 7 restaurants, and a casino. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino are located nearby.
Free airport shuttle
Parking included

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
13639 Riverport Dr Maryland Heights MO
Free cancellation
Reserve now, pay when you stay
106.7 km from Mississippi River
The price is CA $78 per night
CA $78
CA $90 total
Dec 16 - Dec 17
includes taxes & fees
Book a stay at this business-friendly hotel in Maryland Heights. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Hollywood Casino Amphitheatre are located nearby.
Pool
Breakfast included

Motel 6 Hazelwood, MO
5781 Campus Ct Hazelwood MO
Free cancellation
Reserve now, pay when you stay
108.49 km from Mississippi River
The price is CA $84 per night
CA $84
CA $102 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Stay at this motel in Hazelwood. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. Popular attractions Ameristar Casino St. Charles and Bigfoot 4 x 4 Inc are located nearby.
Pet-friendly
Parking included

Pear Tree Inn St. Louis Airport
10810 Pear Tree Ln St. Ann MO
Free cancellation
Reserve now, pay when you stay
112.47 km from Mississippi River
The price is CA $126 per night
CA $126
CA $148 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Payne-Gentry Historical House and Blanche M. Touhill Performing Arts Center are located nearby.
Pool
Breakfast included

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free cancellation
Reserve now, pay when you stay
122.34 km from Mississippi River
The price is CA $138 per night
CA $138
CA $161 total
Dec 13 - Dec 14
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions St. Louis Zoo and Forest Park are located nearby.
Pool
Breakfast included

Forest Park Hotel by MDR
5915 Wilson Ave St. Louis MO
Free cancellation
Reserve now, pay when you stay
127.7 km from Mississippi River
The price is CA $111 per night
CA $111
CA $136 total
Dec 28 - Dec 29
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Pet-friendly
Parking included

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free cancellation
Reserve now, pay when you stay
130.87 km from Mississippi River
The price is CA $213 per night
CA $213
CA $256 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the restaurant in our reviews. Popular attractions St. Louis Union Station and Gateway Arch are located nearby.
Pool
Spa

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
421 N 8th St St. Louis MO
Free cancellation
Reserve now, pay when you stay
131.59 km from Mississippi River
The price is CA $141 per night
CA $141
CA $168 total
Dec 8 - Dec 9
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pet-friendly
Free WiFi

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
Free cancellation
Reserve now, pay when you stay
132.14 km from Mississippi River
The price is CA $132 per night
CA $132
CA $156 total
Jan 2 - Jan 3, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pet-friendly
Free WiFi

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free cancellation
Reserve now, pay when you stay
132.17 km from Mississippi River
The price is CA $189 per night
CA $189
CA $221 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool in our reviews. Popular attractions Gateway Arch and St. Louis Union Station are located nearby.
Pool
Hot tub
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See all available properties in Mississippi River
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Mississippi River Hotels Near Attractions
Do you have a full travel itinerary while visiting Mississippi River? Don't waste your time commuting too far from Mississippi River area attractions.
Mississippi River hotels essential information
Accommodation | 15,249 hotels |
|---|---|
Lowest Price | CA $90 |
Highest Price | CA $256 |
Popular hotels | Pear Tree Inn St. Louis Airport, Magnolia Hotel St. Louis, a Tribute Portfolio Hotel, Hyatt Regency St. Louis at The Arch, Clayton Plaza Hotel & Extended Stay, Ameristar Casino Resort and Spa, Hollywood Casino & Hotel St. Louis, Forest Park Hotel by MDR, Drury Plaza Hotel St. Louis at the Arch, Hampton Inn St. Charles St. Peters, 21C Museum Hotel St Louis , Motel 6 Hazelwood, MO, Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West |
Recent Mississippi River hotel reviews by fellow wanderers

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
5 out of 5
Posted 19 hours ago
Travelocity Verified Review
"Friendly staff "
A verified traveller stayed at Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West





