Find a cheap Hotel in South Central Houston
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Hotels near South Central Houston
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $269 per night from May 27 to May 28
CA $269
CA $377 total
May 27 - May 28
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
"There are a lot of hidden mandatory fees for services that were not used. There is no parking and the valet parking is extremely expensive per day and night. There is no refrigerator or coffee maker in the room. The room looked old."
Reviewed on May 25, 2026
InterContinental Houston by IHG
6750 Main St Houston TX
Fully refundable
The price is CA $225 per night from May 28 to May 29
CA $225
CA $291 total
May 28 - May 29
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
"The hotel was very clean and updated. The staff was very accommodating and attentive. My husband had a surgery at MDAnderaon nearby, so the location was great for me to go back and forth to the hospital and the hotel shuttle service was very convenient to get me to the hospital and back to the hotel. ..."
Reviewed on May 21, 2026
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $223 per night from May 31 to Jun 1
CA $223
CA $277 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
"Rooms clean and enjoyed the bar downstairs."
Reviewed on May 21, 2026
Downtowner Inns - Houston Downtown
2510 Hamilton St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $101 per night from May 27 to May 28
CA $101
CA $118 total
May 27 - May 28
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and Daikin Park are located nearby.
"The room and property were extremely cleaned and very well maintained. The only thing I would’ve liked that wasn’t available was coffee in the room. But, it was easy enough to go to the office and get coffee."
Reviewed on May 22, 2026
Sentral Forme Houston
5501 La Branch Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $247 per night from May 31 to Jun 1
CA $247
CA $330 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this luxury aparthotel in Houston. Enjoy a 24-hour fitness center, parking (surcharge), and a 24-hour front desk. Popular attractions Toyota Center ...
"Great location in the museum district. Friendly staff and easy to get around."
Reviewed on May 24, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $162 per night from Jun 6 to Jun 7
CA $162
CA $192 total
Jun 6 - Jun 7
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
"Breakfast was just okay. Not worth the money. The restaurant for dinner was good. The first night we had a wonderful bartender/waiter, and the food was good. The young gentleman that provided room service with a few items we needed was very prompt and courteous. We had to be moved from our room twice ..."
Reviewed on May 25, 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $159 per night from May 31 to Jun 1
CA $159
CA $185 total
May 31 - Jun 1
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
"Clean and spacious, I loved it. The perfect home from home."
Reviewed on May 25, 2026
Americas Best Value Inn Medical Center Downtown
2419 Riverside Dr Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from May 27 to May 28
CA $115
CA $134 total
May 27 - May 28
includes taxes & fees
Stay at this motel in Houston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
"The price was good, the hotel was near the Museum area, and convenient. The rooms were very clean."
Reviewed on May 18, 2026
Extended Stay America Suites Houston Med Ctr Braeswood Bl
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $101 per night from May 28 to May 29
CA $101
CA $118 total
May 28 - May 29
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
"I had to leave early because the bed wasn't comfortable. I work in the medical center, and the front desk advised I would be refunded for the night's stay. They completely lied. I reached out to Hotels.com multiple times, and they also did nothing to fix the issue. I booked it based on false pictures ..."
Reviewed on May 24, 2026
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Recent South Central Houston hotel reviews by fellow wanderers
Hilton Houston Plaza/Medical Center
3 out of 5
Posted 6 hours ago
Travelocity Verified Review
"Breakfast was just okay. Not worth the money. The restaurant for dinner was good. The first night we had a wonderful bartender/waiter, and the food was good. The young gentleman that provided room service with a few items we needed was very prompt and courteous. We had to be moved from our room twice before we got a room that was not sub-par. The staff at the front desk is what made our stay tolerable. They were all very friendly and super helpful. And one last thing, a quick shout out to the young man that drove the shuttle van. He was very friendly and knowledgeable of things we were interested in."
A verified traveller stayed at Hilton Houston Plaza/Medical Center
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