Find a cheap Hotel in South Central Houston

Start date: Check-in selected.
To Date
End date: Check-out

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Hotels near South Central Houston

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel

2 out of 5
520 Sampson St, Houston, TX
Fully refundableReserve now, pay when you stay
Stay at this hotel in Houston. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Daikin Park and Toyota Center are located nearby.
Great location will stay again

Reviewed on Nov 3, 2025

Opens in a new windowWanderstay Boutique Hotel
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St, Houston, TX
Fully refundable
The price is CA $195 per night from Nov 28 to Nov 29
CA $195
CA $256 total
Nov 28 - Nov 29
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Nice

Reviewed on Nov 11, 2025

Opens in a new windowInterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $192 per night from Nov 29 to Nov 30
CA $192
CA $239 total
Nov 29 - Nov 30
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
Everything about my stay was great and everything went smoothly. Valet was efficient and careful, check-in was easy and the concierge kindly granted my request for a quiet room away from traffic and noise. Room was clean, so nice, and EVERYTHING WORKED (a rarity these days). Terrace 54 Restaurant ...

Reviewed on Nov 10, 2025

Opens in a new windowThe Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $201 per night from Nov 29 to Nov 30
CA $201
CA $279 total
Nov 29 - Nov 30
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy.

Reviewed on Nov 6, 2025

Opens in a new windowHouston Marriott Medical Center/Museum District
Mint House Houston – Medical Center

Mint House Houston – Medical Center

4 out of 5
1911 Holcombe Boulevard, Houston, TX
Stay at this 4-star apartment in Houston. Enjoy free WiFi, a rooftop terrace, and a 24-hour fitness center. Popular attractions Houston Zoo and NRG Stadium are ...
Except for the carpet in the bedroom, the rooms were spotless. Great views. Convenient to MD Anderson and the rest of the Texas Medical Center.

Reviewed on Nov 5, 2025

Opens in a new windowMint House Houston – Medical Center
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $280 per night from Nov 26 to Nov 27
CA $280
CA $385 total
Nov 26 - Nov 27
includes taxes & fees
Stay at this 4.5-star luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
The room was spotless, service was amazing, the food was delicious!

Reviewed on Nov 5, 2025

Opens in a new windowHotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Nov 30 to Dec 1
CA $124
CA $147 total
Nov 30 - Dec 1
includes taxes & fees
Stay at this 4.5-star luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in ...
Thr ac was a bit loud. Otherwise perfection as usual!

Reviewed on Nov 11, 2025

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $150 per night from Nov 27 to Nov 28
CA $150
CA $176 total
Nov 27 - Nov 28
includes taxes & fees
Stay at this 4-star business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Great service

Reviewed on Oct 26, 2025

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2 out of 5
2510 Hamilton St, Houston, TX
Fully refundableReserve now, pay when you stay
The price is CA $133 per night from Nov 13 to Nov 14
CA $133
CA $156 total
Nov 13 - Nov 14
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and Daikin Park are located nearby.
Everything was perfect!

Reviewed on Nov 1, 2025

Opens in a new windowDowntowner Inns - Houston Downtown
Don't see what you're looking for?
See all available properties in South Central Houston
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About South Central Houston Hotels

Search South Central Houston area hotels for the best deals on Travelocity.ca. Zoom in on South Central Houston neighborhood to help narrow your hotel selection.

Get Started - Lets Roam South Central Houston!

Recent South Central Houston hotel reviews by fellow wanderers