Find a cheap Hotel in South Central Houston

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Hotels near South Central Houston

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel

2 out of 5
520 Sampson St Houston TX
The price is CA $164 per night from Jan 11 to Jan 12
CA $164
CA $191 total
Jan 11 - Jan 12
includes taxes & fees
Stay at this hotel in Houston. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Toyota Center and NRG Stadium are located nearby.
The room was adorable and the staff were very friendly and informative.

Reviewed on Dec 20, 2025

Opens in a new windowWanderstay Boutique Hotel
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
The price is CA $215 per night from Jan 18 to Jan 19
CA $215
CA $279 total
Jan 18 - Jan 19
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
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Reviewed on Jan 1, 2026

Opens in a new windowInterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $247 per night from Jan 22 to Jan 23
CA $247
CA $307 total
Jan 22 - Jan 23
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
Yes…all was very nice.

Reviewed on Jan 1, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $209 per night from Jan 23 to Jan 24
CA $209
CA $289 total
Jan 23 - Jan 24
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
Very nice, clean room. No8thing fancy, but not bad at all.

Reviewed on Dec 25, 2025

Opens in a new windowHouston Marriott Medical Center/Museum District
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
Book a stay at this luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
Everything was nice except the pillows, if you can even call them that. Pillows should be trashed.

Reviewed on Jan 2, 2026

Opens in a new windowHotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $128 per night from Jan 11 to Jan 12
CA $128
CA $151 total
Jan 11 - Jan 12
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
We had no problems other than I needed a handicap room/bathroom.

Reviewed on Jan 5, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Feb 1 to Feb 2
CA $115
CA $134 total
Feb 1 - Feb 2
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Everything was top notch

Reviewed on Jan 5, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2 out of 5
2510 Hamilton St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $113 per night from Jan 8 to Jan 9
CA $113
CA $133 total
Jan 8 - Jan 9
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and NRG Stadium are located nearby.
Room was nice, clean and close to midtown

Reviewed on Dec 26, 2025

Opens in a new windowDowntowner Inns - Houston Downtown
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $81 per night from Jan 8 to Jan 9
CA $81
CA $95 total
Jan 8 - Jan 9
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Staff went above and beyond with their attention to details. Rooms were extremely comfortable. The property is located in a very nice area.

Reviewed on Dec 19, 2025

Opens in a new windowExtended Stay America Suites Houston Med Ctr Braeswood Bl
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

South Central Houston Hotel Guide

Don’t keep your travel plans on repeat year after year. The same city with the same hotel every season will bore you and give you an itch to go looking for something new. Expand your geographical horizons to more than just those five blocks around your usual haunt.

Nowhere else can you find better deals on South Central Houston area hotels. You’ll find the best prices on the quirky, the haunted, the old, the new, and the legendary. If you’re wondering what side of the pricing scale some of these hotels fall on, you need not to worry. Compare cheap hotels near South Central Houston to find the perfect one to will fit your budget.

Leave the ordinary routine you’re set on behind and go. Go anywhere you want. Anywhere that makes you think, “I wonder what that’s like?” Part of Travelocity’s mission is to get you off-the-beaten path and the hotels near South Central Houston are perfect for that. Find your new favorite watering hole on a quiet street. Discover a place to escape for the weekend with tasty local fare and unique sights. We want you to consider the places outside your normal comfort zone. Browse our selection and find the ideal hotel, in a place you’d like to explore.

Recent South Central Houston hotel reviews by fellow wanderers