Find a cheap Hotel in South Central Houston

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight
Apr 7 - Apr 8
Tomorrow
Apr 8 - Apr 9
This weekend
Apr 10 - Apr 12
Next weekend
Apr 17 - Apr 19

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Hotels near South Central Houston

InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
The price is CA $238 per night from Apr 10 to Apr 11
CA $238
CA $307 total
Apr 10 - Apr 11
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
Very impressed by the Hotel and price

Reviewed on Apr 7, 2026

Opens in a new windowInterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $237 per night from Apr 18 to Apr 19
CA $237
CA $295 total
Apr 18 - Apr 19
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
I did see a few service pets there.

Reviewed on Apr 5, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $309 per night from Apr 12 to Apr 13
CA $309
CA $426 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
This was a good, hotel in a great district with some very nice amenities. The staff are lovely and the shuttle is fantastic. I didn’t use the pool or spa so can’t speak to this. The rooms are not as luxury boutique as I was expecting but they were certainly comfortable, just a bit in need of renovation- ...

Reviewed on Apr 6, 2026

Opens in a new windowHotel Zaza Houston Museum District
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $249 per night from Apr 25 to Apr 26
CA $249
CA $337 total
Apr 25 - Apr 26
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
Right in the center of the Medical District. Didn’t even have to go outside to get to my wife’s appointment.

Reviewed on Apr 7, 2026

Opens in a new windowHouston Marriott Medical Center/Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $138 per night from Apr 26 to Apr 27
CA $138
CA $163 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
Was given the option to upgrade to a suite and breakfast voucher. Excellent service at the front desk. Good staff at breakfast. Food was exceptional. Loved the Self-park option with room key in and out access. Would HIGHLY recommend this location. Also, decor in the lobby is nice with a small but ...

Reviewed on Apr 5, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $140 per night from Apr 26 to Apr 27
CA $140
CA $164 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
clean, renovated. friendly staff. will stay there again

Reviewed on Apr 6, 2026

Opens in a new windowDoubleTree by Hilton Houston Medical Center Hotel & Suites
Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown

2 out of 5
2510 Hamilton St Houston TX
The price is CA $122 per night from Apr 14 to Apr 15
CA $122
CA $142 total
Apr 14 - Apr 15
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and Daikin Park are located nearby.
Couch was old, room smelled of cigarettes.

Reviewed on Apr 6, 2026

Opens in a new windowDowntowner Inns - Houston Downtown
Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

2 out of 5
2419 Riverside Dr Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $115 per night from Apr 8 to Apr 9
CA $115
CA $135 total
Apr 8 - Apr 9
includes taxes & fees
Stay at this motel in Houston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Positive experience across the board.

Reviewed on Apr 5, 2026

Opens in a new windowAmericas Best Value Inn Medical Center Downtown
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $101 per night from Apr 9 to Apr 10
CA $101
CA $119 total
Apr 9 - Apr 10
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
Clean Tv worked great Hot water

Reviewed on Apr 5, 2026

Opens in a new windowExtended Stay America Suites Houston Med Ctr Braeswood Bl
Don't see what you're looking for?
See all available properties in South Central Houston
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About South Central Houston Hotels

Search South Central Houston area hotels for the best deals on Travelocity.ca. Zoom in on South Central Houston neighborhood to help narrow your hotel selection.

Get Started - Lets Roam South Central Houston!

Recent South Central Houston hotel reviews by fellow wanderers

InterContinental Houston by IHG

InterContinental Houston by IHG

5 out of 5
Posted 14 hours ago
Travelocity Verified Review
"Very impressed by the Hotel and price "
A verified traveller stayed at InterContinental Houston by IHG
InterContinental Houston by IHG

Explore More Ways to Travel with Travelocity