Find a cheap Hotel in Texas Medical Center

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Hotels near Texas Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $174 per night from May 10 to May 11
CA $174
CA $205 total
May 10 - May 11
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
clean comfortable rooms. shuttle service was a great service and saved time and frustration. shuttle driver was very courteous and friendly offering great recommendations for restaurants restaurant.was adequate and cocktails were good

Reviewed on Apr 16, 2026

Opens in a new windowHyatt Place Houston Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $188 per night from Apr 19 to Apr 20
CA $188
CA $234 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
Very pleasant stay with family. Courteous staff, good food, decent fitness center.

Reviewed on Apr 15, 2026

Opens in a new windowThe Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
Fully refundable
The price is CA $224 per night from May 17 to May 18
CA $224
CA $289 total
May 17 - May 18
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
I've stayed at Intercontinental several times in the past including my honeymoon and have had a great experience. However, my experience at the Houston location wasn't as smooth. To start, the bell man was great, he was personable and was ready to help us. We had 4 big luggages and he was ready and ...

Reviewed on Apr 13, 2026

Opens in a new windowInterContinental Houston by IHG
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $188 per night from May 17 to May 18
CA $188
CA $219 total
May 17 - May 18
includes taxes & fees
Book a stay at this spa hotel in Houston. Enjoy a full-service spa, 2 bars/lounges, and a rooftop terrace. Our guests praise the pool and the helpful staff in ...
Great Experience

Reviewed on Apr 16, 2026

Opens in a new windowBlossom Hotel Houston, Curio Collection by Hilton
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $271 per night from Apr 26 to Apr 27
CA $271
CA $379 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
This was such a wonderful experience from the booking, checkin, ambiance, the staff, and the peaceful rest that I received. I will definitely share with friends and plan to return.

Reviewed on Apr 15, 2026

Opens in a new windowHotel Zaza Houston Museum District
The Royal Sonesta Houston Galleria

The Royal Sonesta Houston Galleria

4 out of 5
2222 West Loop South Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $174 per night from May 8 to May 9
CA $174
CA $203 total
May 8 - May 9
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
Pool area was a lil small, but the overall hotel is Great.

Reviewed on Apr 15, 2026

Opens in a new windowThe Royal Sonesta Houston Galleria
Club Quarters Hotel Downtown, Houston

Club Quarters Hotel Downtown, Houston

4 out of 5
1085 Rusk Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Apr 19 to Apr 20
CA $145
CA $169 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and the helpful ...
The place is nice but I have 2 mayor complaints that prevent me from staying there again. First parking. It’s non existent and did this is downtown. And you’ll have to pay 45 for valet or 28 park yourself 2 blocks away. They should include that on description of hotel. Second and worst, noise, lots ...

Reviewed on Apr 15, 2026

Opens in a new windowClub Quarters Hotel Downtown, Houston
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $173 per night from May 10 to May 11
CA $173
CA $205 total
May 10 - May 11
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
Was called handicap room, however my husband who is in a wheelchair, couldn’t get in shower and barely to toilet. No microwave in room, but they did bring one.

Reviewed on Apr 14, 2026

Opens in a new windowHilton Houston Plaza/Medical Center
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $171 per night from May 8 to May 9
CA $171
CA $202 total
May 8 - May 9
includes taxes & fees
Stay at this hotel in Houston. Enjoy an outdoor pool, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff and the clean rooms ...
I was satisfied during my whole stay

Reviewed on Apr 16, 2026

Opens in a new windowDoubleTree by Hilton Hotel & Suites Houston by the Galleria
Don't see what you're looking for?
See all available properties in Texas Medical Center
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

About Texas Medical Center Hotels

Search Texas Medical Center area hotels for the best deals on Travelocity.ca. Zoom in on Texas Medical Center neighborhood to help narrow your hotel selection.

Get Started - Lets Roam Texas Medical Center!

Recent Texas Medical Center hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity