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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Property class: 2.5
Hotel near Market Arcade Building in Buffalo

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

A hotel room with a bed, a TV, a desk, a chair, and a sofa.
A modern hotel lobby with seating areas, large windows, and a view of the outdoors.
A reception desk with a computer, printer, and a vase of flowers.
A modern hotel lobby with green sofas, grey armchairs, and a central table with a vase.
A buffet with labeled containers of omelets and other dishes.

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Convention Center
    ‪6 min walk‬
  • Place, Niagara Square
    ‪8 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

A bed with white bedding and a wooden headboard.

Standard Room

9.2 out of 10
Wonderful
(29 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(64 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

A bathroom with a shower, toilet, and sink.

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

A bathroom with a shower, toilet, and sink.

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

DOUBLE Accessible-Queen Size Bed

  • Sleeps 4
  • Free WiFi

DOUBLE KING SIZE BED

  • Sleeps 4
  • Free WiFi

Room TWO BEDS

  • Sleeps 10
  • Free WiFi

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About the area

Buffalo

Downtown Buffalo stay.With a stay at this Downtown Buffalo hotel, you'll be steps from Buffalo Music Hall of Fame and Market Arcade Building. CEPA Gallery and Buffalo Visitor Center are also within half a mile (1 km).

What's nearby

  • Chippewa District - 1 min walk - 0.0 km
  • Buffalo Visitor Center - 1 min walk - 0.1 km
  • Shea's Performing Arts Center - 2 min walk - 0.2 km
  • Buffalo Convention Center - 6 min walk - 0.6 km
  • Niagara Square - 8 min walk - 0.7 km

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Sidelines Sports Bar and Grill - ‬6 min walk
  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Tim Hortons - ‬7 min walk
  • ‪Garden Grille & Bar - ‬6 min walk
  • ‪Big Ditch Brewing Company - ‬4 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel near Market Arcade Building in Buffalo
Public spaces have free WiFi. You'll find a business center on site. Free breakfast is available daily. A fitness center, a vending machine, and laundry facilities are also featured at the business-friendly Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

This Buffalo hotel is smoke free.

  • 146 guestrooms or units
  • 7 levels
  • Buffet breakfast (free)
  • Business facilities
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Front-desk safe
  • Elevator
  • No smoking on site
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers 146 accommodations with safes and coffee/tea makers. Accommodations have separate sitting areas and are furnished with double sofa beds. Cable television is provided. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations, complimentary toiletries, and hair dryers.

This Buffalo hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

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  • Air conditioning
  • Gym
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includes taxes & fees
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Property amenities

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

Room amenities

Entertainment

  • 49-inch TV with cable channels

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 18 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cribs (infant beds)!

Property payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International, and Carte Blanche. Cash is not accepted. 
    For guests' safety, the property includes a fire extinguisher, a smoke detector, and window guards in each accommodation. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

We should mention

  • Children 18 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to the airport?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is 10.3 mi (21-min drive) away from the Buffalo Niagara Intl. Airport (BUF) airport, the closest popular airport to the property.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of Aug 17, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on Aug 23, 2026 start from CA $169, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have an airport shuttle?

Airport shuttle services are not available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offer free breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast every day from 6:00 AM to 10:00 AM.

Is there a casino at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no casino at this hotel, but Seneca Buffalo Creek Casino (3-min drive) and Hamburg Gaming at the Fairgrounds (19-min drive) are nearby.

What time is check-in at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Check-in start time: 3:00 PM; Check-in end time: anytime.

Is there free parking at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Free parking is not available at this hotel.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a pool?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG does not have a pool.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a spa?

There are no spa services available at this hotel.

How close is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG to downtown Buffalo?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is 0.4 mi away from Buffalo.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 552 out of 1006 reviews
Rating 8 - Good. 268 out of 1006 reviews
Rating 6 - Okay. 84 out of 1006 reviews
Rating 4 - Poor. 44 out of 1006 reviews
Rating 2 - Terrible. 58 out of 1006 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

Verified review

8/10 Good

April

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, nice big rooms!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Jeremiah

Liked: Cleanliness, staff & service, property conditions & facilities
good staff, breakfast was great
Stayed 1 night in May 2026
Verified review

10/10 Excellent

keyhan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room, staff was helpful and breakfast was fresh and delicious
Stayed 3 nights in Apr 2026
Verified review

8/10 Good

Juan

Liked: Cleanliness
Great location
Stayed 4 nights in May 2026
Verified review

10/10 Excellent

Brian

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, quiet. Convenient for my travel. The coffee was great.
Stayed 3 nights in Jun 2026
Verified review

10/10 Excellent

Andy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Affordable and convenient hotel in downtown Buffalo with a good breakfast provided and a spacious room.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Pratik

Clean room and friendly staff. Great location
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Jack

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room ( a bit dated), staff was extremely helpful & breakfast was awesome !
Stayed 3 nights in Apr 2026
Verified review

8/10 Good

Janine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was great and staff was friendly and helpful.
Stayed 2 nights in Mar 2026
Verified review

8/10 Good

Anna

Liked: Cleanliness
Disliked: Staff & service
Convenient location
Stayed 1 night in May 2026
Verified review

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel and great location with an awesome staff. Byron was especially friendly and helpful! Nice breakfast included as well.
Stayed 1 night in Apr 2026
Verified review

6/10 Okay

Patrick

Liked: Cleanliness, staff & service, property conditions & facilities
Good breakfast. Good coffee. Rooms are a good size and comfy. No onsight parking.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Ben

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very well placed hotel for the theatre district in Buffalo as well as a few train stops down from where the Sabers play hockey. Great hotel and an awesome price!!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Scott

Great room and stay for the money.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy and safe area to walk around.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Ryan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Needs a facelift but the place is clean
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Was great
Stayed 1 night in Mar 2026
Verified review

8/10 Good

Corey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was great. Only complaint was the noise from the trolley.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Julie

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room clean most comfortable bed I have ever slept in!
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Sharon

Liked: Cleanliness, amenities, property conditions & facilities
Rooms were very clean. Staff was very accommodating. Just very enjoyable stay.
Stayed 4 nights in Feb 2026
Verified review

10/10 Excellent

Dharani

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff are helpful
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026

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