Find and compare 4 Star hotels in Mestre

Start date: Check-in selected.
To Date
End date: Check-out

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Featured Mestre 4 Star hotels

Hotel Plaza Venice

Hotel Plaza Venice

4 out of 5
Viale Stazione 36 Mestre VE
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,000 reviews)
Modern, comfortable room, accommodating staff and excellent location right across from the train station

Reviewed on Dec 15, 2025

Opens in a new windowHotel Plaza Venice
Annia Park Hotel Venice Airport

Annia Park Hotel Venice Airport

4 out of 5
Via Triestina 161 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $144 per night from Dec 24 to Dec 25
CA $144
CA $168 total
Dec 24 - Dec 25
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (1,002 reviews)
Great service, dinner is a highlight. Francesco was very diligent and made sure I had everything needed for my stay and my travel to the airport.

Reviewed on Dec 21, 2025

Opens in a new windowAnnia Park Hotel Venice Airport
Hotel Cavalletto e Doge Orseolo

Hotel Cavalletto e Doge Orseolo

4 out of 5
Piazza San Marco 1107 Venice VE
Fully refundable
The price is CA $144 per night from Dec 24 to Dec 25
CA $144
CA $173 total
Dec 24 - Dec 25
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,669 reviews)
Room was spacious and clean, but temperature adjustment was out of our control.

Reviewed on Dec 10, 2025

Opens in a new windowHotel Cavalletto e Doge Orseolo
Hotel Saturnia & International

Hotel Saturnia & International

4.5 out of 5
San Marco 2398 - Via XXII Marzo Venice VE
The price is CA $174 per night from Jan 11 to Jan 12
CA $174
CA $202 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the bar in our reviews. ...
9.6/10 Exceptional! (1,004 reviews)
Centrally located near Piazzo San Marco. Family run for generations. Old world charm. Venture to say no two rooms are alike. Water taxis directly at property. Very good bar and restaurant.

Reviewed on Dec 18, 2025

Opens in a new windowHotel Saturnia & International
Hotel Rialto

Hotel Rialto

4 out of 5
San Marco 5149 Ponte Di Rialto Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $150 per night from Jan 14 to Jan 15
CA $150
CA $176 total
Jan 14 - Jan 15, 2026
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,001 reviews)
Good people,

Reviewed on Dec 18, 2025

Opens in a new windowHotel Rialto
Splendid Venice – Starhotels Collezione

Splendid Venice – Starhotels Collezione

4 out of 5
San Marco Mercerie 760 Venice VE
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,003 reviews)
Clean and spacious room

Reviewed on Dec 18, 2025

Opens in a new windowSplendid Venice – Starhotels Collezione
Best Western Plus Hotel Bologna

Best Western Plus Hotel Bologna

4 out of 5
Via Piave 214 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from Jan 4 to Jan 5
CA $136
CA $157 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,001 reviews)
Great room. Very well cleaned, comfortable bed, nicely appointed, even quiet and mostly devoid of street noise. A very good stay,

Reviewed on Nov 30, 2025

Opens in a new windowBest Western Plus Hotel Bologna
Hotel Venice Resort Airport

Hotel Venice Resort Airport

4 out of 5
Via Triestina, 153 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $81 per night from Dec 24 to Dec 25
CA $81
CA $104 total
Dec 24 - Dec 25
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,001 reviews)
Nice hotel with excellent and helpful staff, The property is vast and impressive. The main deterrent are the beds in double rooms which are really tiny. Also, I got a room on the ground floor close to the reception, and the soundproofing was extremely poor with lots of noise coming from the lobby ...

Reviewed on Dec 11, 2025

Opens in a new windowHotel Venice Resort Airport
H10 Palazzo Canova

H10 Palazzo Canova

4.5 out of 5
San Polo - Via Riva del Vin 744 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $238 per night from Jan 15 to Jan 16
CA $238
CA $272 total
Jan 15 - Jan 16, 2026
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,003 reviews)
We were upgraded to a larger room, which was very nice and comfortable. All the amenities were in good order, and the staff was great, particularly with restaurant recommendations. We'd happily come back!

Reviewed on Dec 18, 2025

Opens in a new windowH10 Palazzo Canova
Palazzo Veneziano

Palazzo Veneziano

4.5 out of 5
Fondamenta delle Zattere 1413 Venice VE
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (1,125 reviews)
Clean and quite big room

Reviewed on Dec 15, 2025

Opens in a new windowPalazzo Veneziano
Don't see what you're looking for?
See all available properties in Mestre
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels Mestre

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mestre 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mestre will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mestre, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mestre hotel reviews by fellow wanderers