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Featured Mestre 4 Star hotels

Hotel Plaza Venice

Hotel Plaza Venice

4 out of 5
Viale Stazione 36 Mestre VE
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,001 reviews)
Didn’t have one

Reviewed on Nov 11, 2025

Opens in a new windowHotel Plaza Venice
Annia Park Hotel Venice Airport

Annia Park Hotel Venice Airport

4 out of 5
Via Triestina 161 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $175 per night from Nov 25 to Nov 26
CA $175
CA $202 total
Nov 25 - Nov 26
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (1,000 reviews)
Short visit to Venice before flight home
Hotel staff were very friendly and helpful. Some great recommendations from the front desk staff regarding our visit to Venice. Beautiful room, great location near the airport with easy transportation to Venice’s attractions.

Reviewed on Oct 18, 2025

Opens in a new windowAnnia Park Hotel Venice Airport
Hotel Cavalletto e Doge Orseolo

Hotel Cavalletto e Doge Orseolo

4 out of 5
Piazza San Marco 1107 Venice VE
Fully refundable
The price is CA $172 per night from Nov 26 to Nov 27
CA $172
CA $204 total
Nov 26 - Nov 27
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.6/10 Excellent! (1,671 reviews)
Hermoso .

Reviewed on Nov 15, 2025

Opens in a new windowHotel Cavalletto e Doge Orseolo
Hotel Saturnia & International

Hotel Saturnia & International

4.5 out of 5
San Marco 2398 - Via XXII Marzo Venice VE
The price is CA $177 per night from Dec 18 to Dec 19
CA $177
CA $210 total
Dec 18 - Dec 19
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the breakfast and the bar in our reviews. ...
9.6/10 Exceptional! (1,001 reviews)
Room was perfect as was the service! Would return again!

Reviewed on Nov 10, 2025

Opens in a new windowHotel Saturnia & International
Hotel Rialto

Hotel Rialto

4 out of 5
San Marco 5149 Ponte Di Rialto Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $144 per night from Dec 8 to Dec 9
CA $144
CA $174 total
Dec 8 - Dec 9
includes taxes & fees
Stay at this hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,005 reviews)
Staff were very friendly!

Reviewed on Nov 14, 2025

Opens in a new windowHotel Rialto
Splendid Venice – Starhotels Collezione

Splendid Venice – Starhotels Collezione

4 out of 5
San Marco Mercerie 760 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $274 per night from Dec 18 to Dec 19
CA $274
CA $316 total
Dec 18 - Dec 19
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,002 reviews)
Beautiful hotel, great service

Reviewed on Nov 9, 2025

Opens in a new windowSplendid Venice – Starhotels Collezione
Best Western Plus Hotel Bologna

Best Western Plus Hotel Bologna

4 out of 5
Via Piave 214 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $137 per night from Dec 19 to Dec 20
CA $137
CA $161 total
Dec 19 - Dec 20
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the breakfast and the ...
9.2/10 Wonderful! (1,001 reviews)
Spacious, clean room, comfortable bed. In walking distance to many places to eat and publuc transportation.

Reviewed on Nov 15, 2025

Opens in a new windowBest Western Plus Hotel Bologna
Hotel Venice Resort Airport

Hotel Venice Resort Airport

4 out of 5
Via Triestina, 153 Mestre VE
Fully refundableReserve now, pay when you stay
The price is CA $60 per night from Nov 27 to Nov 28
CA $60
CA $80 total
Nov 27 - Nov 28
includes taxes & fees
Book a stay at this business-friendly hotel in Mestre. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.2/10 Very Good! (1,003 reviews)
Excelente lugar gracias

Reviewed on Nov 12, 2025

Opens in a new windowHotel Venice Resort Airport
H10 Palazzo Canova

H10 Palazzo Canova

4.5 out of 5
San Polo - Via Riva del Vin 744 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $267 per night from Dec 14 to Dec 15
CA $267
CA $308 total
Dec 14 - Dec 15
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,002 reviews)
The staff were fantastic. Room very nice and I’d stay again.

Reviewed on Nov 14, 2025

Opens in a new windowH10 Palazzo Canova
Palazzo Veneziano

Palazzo Veneziano

4.5 out of 5
Fondamenta delle Zattere 1413 Venice VE
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the breakfast and the helpful staff in our ...
9.6/10 Exceptional! (1,104 reviews)
Easy to get to by Boat Taxi, friendly staff.

Reviewed on Nov 17, 2025

Opens in a new windowPalazzo Veneziano
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4 Star Hotels Mestre

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in Mestre 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in Mestre will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in Mestre, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent Mestre hotel reviews by fellow wanderers