Book Exclusive Depew Vacation Packages

Choose one or more items to build your trip:

Depew flight + hotel packages

Price found within the past 48 hours. Click for updated prices.
Seneca Niagara Resort & Casino

Seneca Niagara Resort & Casino

4 out of 5
Downtown Niagara Falls
per person
Jul. 26 - Jul. 29
Roundtrip flight included
Vancouver (YVR) to Buffalo (BUF)
Stay at this 4-star spa hotel in Niagara Falls. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Seneca Niagara Resort & Casino and Fallsview Indoor Waterpark are located nearby.
Kalika Hotel

Kalika Hotel

2 out of 5
Downtown Niagara Falls
per person
Jul. 26 - Jul. 29
Roundtrip flight included
Vancouver (YVR) to Buffalo (BUF)
Stay at this hotel in Niagara Falls. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Seneca Niagara Resort & Casino and Niagara Falls State Park are located nearby.
Niagara Riverside Resort, BW Premier Collection

Niagara Riverside Resort, BW Premier Collection

3.5 out of 5
per person
Jul. 26 - Jul. 29
Roundtrip flight included
Vancouver (YVR) to Buffalo (BUF)
Book a stay at this business-friendly hotel in Niagara Falls. Enjoy free WiFi, breakfast (surcharge), and a health club. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Seneca Niagara Resort & Casino and Fallsview Indoor Waterpark are located nearby.
La Quinta Inn & Suites by Wyndham Niagara Falls

La Quinta Inn & Suites by Wyndham Niagara Falls

2.5 out of 5
per person
Jul. 26 - Jul. 29
Roundtrip flight included
Vancouver (YVR) to Buffalo (BUF)
Stay at this hotel in Niagara Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Seneca Niagara Resort & Casino and Fallsview Indoor Waterpark are located nearby.
Niagara Crossing Hotel & Spa

Niagara Crossing Hotel & Spa

3.5 out of 5
per person
Jul. 26 - Jul. 29
Roundtrip flight included
Vancouver (YVR) to Buffalo (BUF)
Stay at this 3.5-star spa hotel in Lewiston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Fallsview Indoor Waterpark and Clifton Hill are located nearby.

Top Depew hotels deals

Comfort Inn & Suites Buffalo Airport

Comfort Inn & Suites Buffalo Airport

3 out of 5
4345 Genesee St, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
The price is CA $150 per night
CA $150
per night
May 29 - May 30
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Walden Galleria Mall and Diamond Hawk Golf Course are located nearby.
M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
The price is CA $119 per night
CA $119
per night
May 14 - May 15
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Walden Galleria Mall and Buffalo Zoo are located nearby.
Niagara Riverside Resort, BW Premier Collection

Niagara Riverside Resort, BW Premier Collection

3.5 out of 5
7001 Buffalo Ave, Niagara Falls, NY
Free cancellation
Reserve now, pay when you stay
The price is CA $135 per night
CA $135
per night
May 19 - May 20
Book a stay at this business-friendly hotel in Niagara Falls. Enjoy free WiFi, breakfast (surcharge), and a health club. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Seneca Niagara Resort & Casino and Fallsview Indoor Waterpark are located nearby.
Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

2.5 out of 5
1601 Amherst Manor Drive, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
The price is CA $162 per night
CA $162
per night
May 27 - May 28
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Buffalo Zoo and Walden Galleria Mall are located nearby.
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
The price is CA $129 per night
CA $129
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the bar in our reviews. Popular attractions Walden Galleria Mall and Diamond Hawk Golf Course are located nearby.
Holiday Inn Express Grand Island - Niagara Falls, an IHG Hotel

Holiday Inn Express Grand Island - Niagara Falls, an IHG Hotel

2.5 out of 5
2761 Long Road, Grand Island, NY
Free cancellation
The price is CA $149 per night
CA $149
per night
May 12 - May 13
Book a stay at this business-friendly hotel in Grand Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Niagara Falls State Park and Horseshoe Falls are located nearby.
Don't see what you're looking for?
See all available properties in Depew
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Image for University At Buffalo - North Campus

University At Buffalo - North Campus

4/5(16 reviews)

Explore the campus of University At Buffalo - North Campus, a top college in Amherst. Experience the area's great live music and acclaimed theater scene.

University At Buffalo - North Campus
Image for Bills Stadium

Bills Stadium

4/5(363 reviews)

Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's great live music and entertainment choices.

Bills Stadium
Image for Buffalo Zoo

Buffalo Zoo

3.5/5(286 reviews)

Why not visit the native and exotic animals who live at Buffalo Zoo during your trip to Buffalo? Experience the area's great live music and entertainment choices.

Buffalo Zoo

Depew Vacations

Collect new memories, embark on incredible adventures and follow the path less traveled — it's all possible in Depew. But first, let us fill you in on a few basic facts about your next travel destination!

A neighborhood in the fabulous city of Buffalo, Depew is 9 miles (14 kilometers) to the east of the center.

Ready to meet the locals? 260,000 people call Buffalo home.

Places to visit in Depew

Dress in your finest khakis and grab hold of your lucky putter. If you're eager to get outside for an afternoon on the green, reserve a tee time at Diamond Hawk Golf Course. Want some more nearby options? The intimacy and mastery of live theater is difficult to ignore. Purchase your tickets for a play at Lancaster Opera House and feel the magic for yourself! And there's more. Pick up some crackers, cheese and a cold drink and enjoy a picnic at Stiglmeier Park. It's one of the best spots to plonk yourself down and while away a few hours.

Where do you fly into for Depew?

Landing at Buffalo Niagara International Airport (BUF)? Depew is only 2 miles (3 kilometers) from here. Grab a cup of coffee, jump in a cab and you'll be there in no time at all!

Frequently asked questions

How much are vacation packages to Depew?
Packages, which provide both flights and hotels in Depew, start from as low as CA $874. Make your travel fantasies come to life and book your trip with Travelocity today.
Where can I get the best vacation package deals for Depew?
You can pick up unbeatable Depew package deals with Travelocity. Mix and match from 400 air carriers and 665,000 worldwide properties and turn those vacation dreams into a reality.
Why should I book my Depew vacation package with Travelocity?
With superb service, support available 24/7 and some of the most gorgeous escapes imaginable, you’ll never roam alone. And if you find a better price, we’ll match it. That’s our Price Match Guarantee.
Will I save money on my Depew car rental if I book it with hotels and flights?
Booking a Depew vacation package with Travelocity is a surefire way to save your hard-earned money. You can choose a flight, car and hotel, or any combination of them, and land awesome discounts. You might also want to add on experiences. After you’ve picked up the keys to your rental car, head out of the neighborhood and see what the area has to offer. About 190 kilometersfrom Depew, Conneaut Railroad Museum is certainly worth a road trip.
What is the best time of year to go to Depew?
is peak season here, while are usually quieter. If your budget is your main consideration, try to avoid traveling during as it tends to be the dearest time. The cheapest month to see this part of the world is .
Where should I stay when visiting Depew?
After a big day of sightseeing around Depew, rest your head at the Depew Apartment W/yard - 35 Mins to Niagara Falls!. This popular option has everything you need for a pleasant stay.
Can I go on vacation to Depew at this time?
Find out all the info you need to know about travel restrictions and quarantine policies before you head for Depew. Our Covid-19 Travel Advisor is full of useful advice to help make your trip as hassle-free as possible.