Book Cheap Hotels in Depew
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Most frequently booked Depew hotels

M Hotel Buffalo
2040 Walden Ave, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
4.63 km from city centre
The price is CA $123 per night
CA $123
CA $140 total
Sep 16 - Sep 17
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Walden Galleria Mall and Buffalo Zoo are located nearby.
Pool
Breakfast included

Buffalo Airport Hotel
4600 Genesee St, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
4.01 km from city centre
The price is CA $101 per night
CA $101
CA $114 total
Aug 27 - Aug 28
includes taxes & fees
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free WiFi, free parking, and a free airport shuttle. Our guests praise the restaurant and the bar in our reviews. Popular attractions Walden Galleria Mall and Diamond Hawk Golf Course are located nearby.
Free airport shuttle
Parking included

Hyatt Regency Buffalo / Hotel and Conference Center
Two Fountain Plaza, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
13.89 km from city centre
The price is CA $175 per night
CA $175
CA $200 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions KeyBank Center and Buffalo Zoo are located nearby.
Pool
Pet-friendly

Holiday Inn Express Grand Island - Niagara Falls by IHG
2761 Long Road, Grand Island, NY
Free cancellation
Reserve now, pay when you stay
28.76 km from city centre
The price is CA $147 per night
CA $147
CA $167 total
Sep 14 - Sep 15
includes taxes & fees
Book a stay at this business-friendly hotel in Grand Island. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Seneca Niagara Resort & Casino and Niagara Falls State Park are located nearby.
Pool
Breakfast included

Comfort Inn University
1 Flint Rd, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
12.27 km from city centre
The price is CA $146 per night
CA $146
CA $167 total
Sep 1 - Sep 2
includes taxes & fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Buffalo Zoo and Walden Galleria Mall are located nearby.
Pool
Breakfast included

Garden Place Hotel
6615 Transit Road, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
5.27 km from city centre
Stay at this 3.5-star business-friendly hotel in Buffalo. Enjoy free parking, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff and the convenient parking in our reviews. Popular attractions Walden Galleria Mall and Diamond Hawk Golf Course are located nearby.
Free airport shuttle
Pet-friendly

Sleep Inn & Suites Buffalo Airport
100 Holtz Dr, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
4.22 km from city centre
The price is CA $121 per night
CA $121
CA $137 total
Sep 8 - Sep 9
includes taxes & fees
Book a stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Walden Galleria Mall and Diamond Hawk Golf Course are located nearby.
Breakfast included
Free airport shuttle

La Quinta Inn & Suites by Wyndham Buffalo Amherst
145 Innkeepers Lane, Buffalo, NY
Free cancellation
Reserve now, pay when you stay
14.82 km from city centre
The price is CA $144 per night
CA $144
CA $164 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 3-star business-friendly hotel in Buffalo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Buffalo Zoo and Boulevard Place are located nearby.
Pool
Breakfast included

Comfort Inn & Suites Niagara Falls Blvd USA
6115 Niagara Falls Blvd, Niagara Falls, NY
Free cancellation
Reserve now, pay when you stay
31.53 km from city centre
The price is CA $128 per night
CA $128
CA $146 total
Sep 14 - Sep 15
includes taxes & fees
Book a stay at this business-friendly hotel in Niagara Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Seneca Niagara Resort & Casino and Niagara Falls State Park are located nearby.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top hotels in Depew for Extended Stay

1 Bedroom | Free Breakfast, Pool and Gym Access
Amherst
The price is CA $274 per night from Aug 27 to Aug 28
CA $274
CA $357 total
Aug 27 - Aug 28
includes taxes & fees
10/10 Exceptional! (1 review)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Depew hotels essential information
Accommodation | 823 hotels |
---|---|
Lowest Price | CA $101 |
Highest Price | CA $297 |
Popular hotels | M Hotel Buffalo, Buffalo Airport Hotel, Hyatt Regency Buffalo / Hotel and Conference Center, Holiday Inn Express Grand Island - Niagara Falls by IHG, Comfort Inn University, Garden Place Hotel, Sleep Inn & Suites Buffalo Airport, La Quinta Inn & Suites by Wyndham Buffalo Amherst, Comfort Inn & Suites Niagara Falls Blvd USA |
Frequently asked questions
Recent Depew hotel reviews by fellow wanderers

Comfort Inn University
5 out of 5
Posted 13 hours ago
Travelocity Verified Review
"I had an amazing stay at this hotel! The staff were incredibly welcoming and always ready to help with a smile. The room was spotless, spacious, and very comfortable, with all the little details thought of. The location was perfect—close to everything I needed, yet quiet enough to relax. I especially enjoyed the breakfast, which had a great variety and was fresh every morning. Overall, the service and atmosphere made me feel truly cared for, and I’ll definitely be coming back on my next trip.
"
A verified traveller stayed at Comfort Inn University
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