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Hotels near Medical Center District
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $162 per night from Feb 8 to Feb 9
CA $162
CA $192 total
Feb 8 - Feb 9
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Our favorite riverwalk hotel. Love the location and the buffet.
Reviewed on Feb 1, 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Great place, room was very clean, place was super nice, walking distance to everything 💪
Reviewed on Feb 1, 2026
Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Feb 9 to Feb 10
CA $147
CA $174 total
Feb 9 - Feb 10
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
Beautiful hotel with great history. Was a bit cold due to crazy cold weather. Staff was excellent!
Reviewed on Jan 31, 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
Fully refundable
The price is CA $103 per night from Mar 1 to Mar 2
CA $103
CA $178 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
Great place. The room was wonderful, comfortable, clean. The bed was very comfortable which I’m very picky about. The steam was the best part. The pool was heated. I wasn’t able to enjoy all the grounds has to offer due to freezing weather. But was able to get into the pool because it was nice and ...
Reviewed on Jan 28, 2026
Crockett Hotel
320 Bonham San Antonio TX
The price is CA $139 per night from Feb 9 to Feb 10
CA $139
CA $164 total
Feb 9 - Feb 10
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant ...
Eduardo was incredible. Had a problem with the rooms heat and it was made right immediately. Will stay here again.
Reviewed on Jan 27, 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Feb 3 to Feb 4
CA $121
CA $143 total
Feb 3 - Feb 4
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
THE TRIP PACKAGE WAS WHAT I WANTED . PRICING WAS REASONABLE. PLEASE KEEP UP THE GOOD WORK
Reviewed on Feb 1, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $138 per night from Feb 6 to Feb 7
CA $138
CA $164 total
Feb 6 - Feb 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
Courteous staff, clean room, safe location
Reviewed on Jan 30, 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
Naomi at least he bar/restaurant was the hilite of the hotel
Reviewed on Jan 31, 2026
Park Inn by Radisson
7500 Louis Pasteur Drive San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $87 per night from Mar 1 to Mar 2
CA $87
CA $101 total
Mar 1 - Mar 2
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
The a/c kept the room nice and warm.
Reviewed on Jan 23, 2026
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Recent Medical Center District hotel reviews by fellow wanderers
Hotel Valencia Riverwalk
5 out of 5
Posted 10 hours ago
Travelocity Verified Review
"Great place, room was very clean, place was super nice, walking distance to everything 💪"
A verified traveller stayed at Hotel Valencia Riverwalk
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