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Hotels near Medical Center District
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Beautiful room. However, the toilet had issues, no mini fridge or microwave in the room. For this nice of a hotel you would expect those amenities. Also wish there was elevator access from the river up to the lobby of the hotel to make it safer for guests. The best part of the hotel was the valet ...
Reviewed on Feb 8, 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
Fully refundable
The price is CA $104 per night from Mar 1 to Mar 2
CA $104
CA $179 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
Fabulous amenities, attentive staff, clean comfortable rooms
Reviewed on Feb 10, 2026
Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $119 per night from Feb 23 to Feb 24
CA $119
CA $140 total
Feb 23 - Feb 24
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
Amazing
Reviewed on Feb 13, 2026
Crockett Hotel
320 Bonham San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Feb 23 to Feb 24
CA $121
CA $144 total
Feb 23 - Feb 24
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, valet parking (surcharge), and a 24-hour front desk. Our guests praise the pool and the restaurant ...
Room was clean except for some stains on carpet. Bathroom was clean but Faucets in tub and sink were dripping water pressure was very good.staff was friendly and helpful. Location is excellent can walk anywhere
Reviewed on Feb 7, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from Feb 20 to Feb 21
CA $136
CA $162 total
Feb 20 - Feb 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
Staff was courteous. AC was very loud.
Reviewed on Feb 9, 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $121 per night from Feb 15 to Feb 16
CA $121
CA $143 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Very courteous and helpful staff at front desk.
Reviewed on Feb 2, 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
Nice view
Reviewed on Feb 13, 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $97 per night from Feb 15 to Feb 16
CA $97
CA $141 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Room was clean and breakfast was really good. Lots of waffle makers and coffee pots. Easy walk to River Walk or to Convention Center. Will definitely stay here again.
Reviewed on Feb 7, 2026
Park Inn by Radisson
7500 Louis Pasteur Drive San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $96 per night from Mar 16 to Mar 17
CA $96
CA $112 total
Mar 16 - Mar 17
includes taxes & fees
Stay at this motel in San Antonio. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
Room was clean and I enjoyed it.
Reviewed on Feb 4, 2026
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Get Started - Lets Roam Medical Center District!
Recent Medical Center District hotel reviews by fellow wanderers
Riverwalk Plaza
5 out of 5
Posted 11 hours ago
Travelocity Verified Review
"Nice view"
A verified traveller stayed at Riverwalk Plaza
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