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Hotels near Medical Center District

Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
First and foremost we have stayed at many of the other hotels on or real the Riverwalk and while we usually have our "usual" we decided to try this one out. The Lobby, staff, services and food were all absolutely incredible and the initial ambiance and check in were very inviting. The room was spacious ...
Reviewed on Dec 2, 2025

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $166 per night from Dec 14 to Dec 15
CA $166
CA $196 total
Dec 14 - Dec 15
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Breakfast subpar
Reviewed on Dec 3, 2025

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
Fully refundable
The price is CA $105 per night from Jan 5 to Jan 6
CA $105
CA $181 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
Great place!
Reviewed on Dec 5, 2025

Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $130 per night from Dec 17 to Dec 18
CA $130
CA $153 total
Dec 17 - Dec 18
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
The room was spotless and all staff were helpful and polite. We love this Hotel.
Reviewed on Dec 3, 2025

La Quinta Inn & Suites by Wyndham San Antonio Downtown
100 W. Cesar Chavez Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Dec 22 to Dec 23
CA $122
CA $144 total
Dec 22 - Dec 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Good
Reviewed on Dec 3, 2025

Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Dec 16 to Dec 17
CA $123
CA $145 total
Dec 16 - Dec 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Staff and cleanliness
Reviewed on Dec 4, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Dec 10 to Dec 11
CA $123
CA $145 total
Dec 10 - Dec 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Room was very neatly clean. Gym is good although one of treadmill does not work. Breakfast is good. Staff: very friendly.
Reviewed on Dec 2, 2025

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from Dec 11 to Dec 12
CA $123
CA $146 total
Dec 11 - Dec 12
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
Overall great. However, phone didn’t work. No conditioner in bottle. half roll of toilet paper to use and had to use it sparingly. Don’t care where the AC is stationed. Little things that didn’t make it so bad at all. Thank you.
Reviewed on Dec 3, 2025

Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
The beds werent
Reviewed on Dec 3, 2025
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Recent Medical Center District hotel reviews by fellow wanderers

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
5 out of 5
Posted 3 days ago
Travelocity Verified Review
"Great place!"
A verified traveller from Willis stayed at Hyatt Vacation Club at Wild Oak Ranch, San Antonio
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