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Hotels near Medical Center District
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $176 per night from Jun 14 to Jun 15
CA $176
CA $208 total
Jun 14 - Jun 15
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Figured they’d have Q-tips and lotions in the room and they didn’t that would’ve been helpful Also, pool was too small for as many guests that would go in it along with the hot tubs
Reviewed on May 17, 2026
Hotel Contessa
306 W Market Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $159 per night from Jun 7 to Jun 8
CA $159
CA $225 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, an outdoor pool, and a full-service spa. Our guests praise the breakfast and the pool in our reviews. ...
Staff amazing. Bar staff not so great. Bathroom had mold. Great bed.
Reviewed on May 17, 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from May 24 to May 25
CA $135
CA $159 total
May 24 - May 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
When I checked for a week and payed CASH IN TOWN FOR A MILITARY EVENT AT LACKLAND AFB DRIVE 25 hours, NO ONE INFORMED ME IF I HAD TO LEAVE EARLY I NEED TO GIVE A NOTICE OR THE HOTEL WOULD RETAIN A FEE OF 129.00. It just not a way to handle playing customers of over 25 years!
Reviewed on May 8, 2026
Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $112 per night from May 19 to May 20
CA $112
CA $133 total
May 19 - May 20
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
Check-in was poor. The rooms don’t compare to the Crockett across the street. They’re tiny. The bathroom smelled of mold and mildew. I can only assume it wasn’t clean. There were no amenities to speak of the restaurant was closed.
Reviewed on May 17, 2026
Hyatt Regency Hill Country Resort and Villas
9800 Hyatt Resort Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $466 per night from May 20 to May 21
CA $466
CA $659 total
May 20 - May 21
includes taxes & fees
Book a stay at this golf hotel in San Antonio. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the helpful staff and the clean rooms in ...
Gorgeous place and jacob at the desk sang happy birthday to my wife upon check in! Beautiful stay!
Reviewed on Apr 28, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from May 29 to May 30
CA $139
CA $165 total
May 29 - May 30
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
The hotel’s location is great. The reception staff was welcoming and friendly, and the rooms are always clean.
Reviewed on May 11, 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from May 19 to May 20
CA $122
CA $144 total
May 19 - May 20
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
The bed was comfy and there was a microwave and fridge in the room. Not the case for most hotels these days. Having to go to the lobby to heat food is a pain!
Reviewed on May 17, 2026
Sonesta ES Suites San Antonio Downtown Alamo Plaza
425 Bonham San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from May 19 to May 20
CA $139
CA $164 total
May 19 - May 20
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Stay was good. 2 bedroom was the best idea
Reviewed on May 17, 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $123 per night from May 19 to May 20
CA $123
CA $145 total
May 19 - May 20
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
Good location. Well priced but walls were very thin and could hear conversation from even several doors down
Reviewed on May 17, 2026
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Recent Medical Center District hotel reviews by fellow wanderers
Drury Plaza Hotel San Antonio Riverwalk
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Figured they’d have Q-tips and lotions in the room and they didn’t that would’ve been helpful
Also, pool was too small for as many guests that would go in it along with the hot tubs"
A verified traveller stayed at Drury Plaza Hotel San Antonio Riverwalk
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