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Hotels near Medical Center District

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $182 per night from Jul 9 to Jul 10
CA $182
CA $215 total
Jul 9 - Jul 10
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
"Excellent location using the city street. Loved the breakfast and the dinner availability. Staff is great especially Theresa at the front desk! Everything you need is there."
Reviewed on Jul 3, 2026

Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $167 per night from Jul 10 to Jul 11
CA $167
CA $238 total
Jul 10 - Jul 11
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
"Was one of the best hotels yet we come to San Antonio a lot and this was a pleasure to be here we will be back"
Reviewed on Jul 3, 2026

Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $128 per night from Jul 12 to Jul 13
CA $128
CA $151 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
"All the staff was super nice and the room looks great."
Reviewed on Jul 2, 2026

JW Marriott San Antonio Hill Country Resort & Spa
23808 Resort Pkwy San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $538 per night from Jul 8 to Jul 9
CA $538
CA $733 total
Jul 8 - Jul 9
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy 4 outdoor pools, a full-service spa, and 6 restaurants. Our guests praise the helpful staff in our reviews. ...
"Everything about it was amazing!"
Reviewed on Jul 3, 2026

Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Jul 10 to Jul 11
CA $126
CA $149 total
Jul 10 - Jul 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
"Staff was awesome helping me when my husband accidentally left the room key in the room."
Reviewed on Jul 3, 2026

Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from Jul 15 to Jul 16
CA $136
CA $161 total
Jul 15 - Jul 16
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
"Historic buildings"
Reviewed on Jul 3, 2026

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from Jul 12 to Jul 13
CA $165
CA $196 total
Jul 12 - Jul 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
"Very nice hotel Had a great experience"
Reviewed on Jul 2, 2026

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Jul 5 to Jul 6
CA $126
CA $149 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
"Staff is very kind and helpful. The room was clean and the bed was comfy."
Reviewed on Jul 3, 2026

Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Jul 5 to Jul 6
CA $127
CA $150 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
"Our ac froze up in our room most of the night. A member of the maintenance department sent me a message through the hotel email system and I know it was him by what he had called me because he tried to make a joke out of my first part of my name while we checked in. Very creepy and uncomfortable. ..."
Reviewed on Jul 3, 2026
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Recent Medical Center District hotel reviews by fellow wanderers

Menger Hotel
5 out of 5
Posted 7 hours ago
Travelocity Verified Review
"Historic buildings"
A verified traveller stayed at Menger Hotel
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