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Hotels near Medical Center District
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from Jan 11 to Jan 12
CA $165
CA $195 total
Jan 11 - Jan 12
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Very friendly staff. Great Riverwaklk location.
Reviewed on Jan 2, 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $302 per night from Jan 17 to Jan 18
CA $302
CA $389 total
Jan 17 - Jan 18
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
Amazing hotel
Reviewed on Jan 2, 2026
Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
Fully refundable
The price is CA $99 per night from Jan 26 to Jan 27
CA $99
CA $174 total
Jan 26 - Jan 27
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
Fabulous room!! Wish we had more time to spend here! Lots of things to do.. pool, lazy River, etc
Reviewed on Jan 5, 2026
Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $138 per night from Jan 8 to Jan 9
CA $138
CA $163 total
Jan 8 - Jan 9
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
Beautiful Hotel and close to everything downtown and Riverwalk
Reviewed on Jan 2, 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Jan 8 to Jan 9
CA $122
CA $145 total
Jan 8 - Jan 9
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Clean room and nice staff
Reviewed on Jan 1, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $151 per night from Jan 16 to Jan 17
CA $151
CA $179 total
Jan 16 - Jan 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
It was a great stay nothing to complain about. Liked the service, cleanliness.
Reviewed on Dec 29, 2025
Sonesta ES Suites San Antonio Downtown Alamo Plaza
425 Bonham San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $118 per night from Jan 25 to Jan 26
CA $118
CA $140 total
Jan 25 - Jan 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
Location was great. Room was great. No sure why when you book two rooms they made them as far apart as they could. At least the rooms were on same floor. Breakfast wasn't anything to write about. I was expecting more. Parking was a little on the pricey side at $50 a night which is more than i use ...
Reviewed on Jan 2, 2026
Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
Confortable and well located.
Reviewed on Jan 2, 2026
La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $104 per night from Jan 14 to Jan 15
CA $104
CA $147 total
Jan 14 - Jan 15
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Good
Reviewed on Jan 3, 2026
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Recent Medical Center District hotel reviews by fellow wanderers
The Westin Riverwalk, San Antonio
5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Great location by the river. Rooms were immaculate. Will come again"
A verified traveller stayed at The Westin Riverwalk, San Antonio
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