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Hotels near Medical Center District
Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $179 per night from Aug 18 to Aug 19
CA $179
CA $212 total
Aug 18 - Aug 19
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
"Great hotel and staff. This is our go to Hotel every time we’re in San Antonio."
Reviewed on Jul 18, 2026
Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from Jul 21 to Jul 22
CA $158
CA $227 total
Jul 21 - Jul 22
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean ...
"Very nice hotel and comfortable beds. Wasn’t aware there was no hotel parking, didn’t mind going down the street for $9 as they were charging $65 for valet, that was a bit much."
Reviewed on Jul 17, 2026
Drury Inn & Suites San Antonio Northwest Medical Center
9806 Interstate Hwy 10 W San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Aug 2 to Aug 3
CA $126
CA $149 total
Aug 2 - Aug 3
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
"One of the main elevators was not working so the other elevator was so crowded, also hotel is noisy with car noise passing in the highway nearby."
Reviewed on Jul 18, 2026
Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Aug 7 to Aug 8
CA $125
CA $148 total
Aug 7 - Aug 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
"Would recommend it was very clean and the view was amazing. No breakfast"
Reviewed on Jul 17, 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $125 per night from Jul 20 to Jul 21
CA $125
CA $147 total
Jul 20 - Jul 21
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
"Special thanks to ever employed that had served me I have no complaints and I enjoyed it so much that I can’t wait to come back again"
Reviewed on Jul 18, 2026
Spark By Hilton San Antonio Northwest near Six Flags
6755 North Loop 1604 West San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $90 per night from Aug 10 to Aug 11
CA $90
CA $108 total
Aug 10 - Aug 11
includes taxes & fees
Stay at this hotel in San Antonio. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the clean rooms in our reviews. Popular attractions ...
"Clean room However the room was not quite because there was a contribution and it was noisy."
Reviewed on Jul 18, 2026
San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $149 per night from Aug 17 to Aug 18
CA $149
CA $177 total
Aug 17 - Aug 18
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy room service, a 24-hour fitness center, and WiFi (surcharge). Our guests praise the helpful ...
Hyatt Regency San Antonio Riverwalk
123 Losoya St San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $213 per night from Aug 6 to Aug 7
CA $213
CA $298 total
Aug 6 - Aug 7
includes taxes & fees
Book a stay at this spa hotel in San Antonio. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the clean rooms ...
Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $120 per night from Jul 20 to Jul 21
CA $120
CA $142 total
Jul 20 - Jul 21
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
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Recent Medical Center District hotel reviews by fellow wanderers
Drury Plaza Hotel San Antonio Riverwalk
5 out of 5
Posted less than an hour ago
Travelocity Verified Review
"Great hotel and staff. This is our go to Hotel every time we’re in San Antonio."
A verified traveller stayed at Drury Plaza Hotel San Antonio Riverwalk
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