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Hotels near Palmdale Regional Medical Center

Holiday Inn Palmdale-Lancaster by IHG
38630 5th St W Palmdale CA
Free cancellation
0.75 km from Palmdale Regional Medical Center
The price is CA $127 per night
CA $127
CA $143 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Palmdale. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Antelope Valley Country Club and Palmdale Playhouse are located nearby.

DoubleTree by Hilton Palmdale, CA
West Palmdale Boulevard, 300 Palmdale CA
Free cancellation
Reserve now, pay when you stay
1.05 km from Palmdale Regional Medical Center
The price is CA $114 per night
CA $114
CA $128 total
Jan 9 - Jan 10, 2026
includes taxes & fees
Book a stay at this family-friendly hotel in Palmdale. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Palmdale Playhouse and Antelope Valley Country Club are located nearby.

Wyndham Garden Lancaster CA
2038 W Avenue I Lancaster CA
Free cancellation
Reserve now, pay when you stay
13.69 km from Palmdale Regional Medical Center
The price is CA $138 per night
CA $138
CA $153 total
Jan 3 - Jan 4, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Lancaster. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Hangar Stadium and The Hangar - Lancaster Jethawks are located nearby.
Pool
Hot tub

Triplodge of Santa Clarita
17843 Sierra Hwy Canyon Country CA
Free cancellation
Reserve now, pay when you stay
32.67 km from Palmdale Regional Medical Center
The price is CA $149 per night
CA $149
CA $164 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Canyon Country. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Canyon Country Park and Regal Edwards Canyon Country are located nearby.

Travelodge by Wyndham Sylmar CA
14955 Roxford St Sylmar CA
Free cancellation
Reserve now, pay when you stay
40.76 km from Palmdale Regional Medical Center
The price is CA $131 per night
CA $131
CA $153 total
Jan 6 - Jan 7, 2026
includes taxes & fees
Stay at this motel in Sylmar. Enjoy free WiFi, free parking, and cable TV channels. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Nethercutt Collection and Nethercutt Museum are located nearby.

Santa Clarita Motel
24971 Railroad Ave. Newhall CA
Free cancellation
Reserve now, pay when you stay
41.59 km from Palmdale Regional Medical Center
The price is CA $105 per night
CA $105
CA $119 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly motel in Newhall. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Six Flags Magic Mountain and Laemmle Theatres Newhall are located nearby.

Hotel Lexen - Newhall
24219 Railroad Avenue Newhall CA
Free cancellation
Reserve now, pay when you stay
41.6 km from Palmdale Regional Medical Center
The price is CA $157 per night
CA $157
CA $176 total
Jan 5 - Jan 6, 2026
includes taxes & fees
Stay at this hotel in Newhall. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Six Flags Magic Mountain and Laemmle Theatres Newhall are located nearby.

Hyatt Regency Valencia
24500 Town Center Drive Valencia CA
Free cancellation
Reserve now, pay when you stay
42.35 km from Palmdale Regional Medical Center
The price is CA $208 per night
CA $208
CA $233 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Valencia. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Six Flags Magic Mountain and The Ivy Day Spa are located nearby.

Best Western Valencia/Six Flags Inn & Suites
27513 Wayne Mills Place Valencia CA
Free cancellation
Reserve now, pay when you stay
43.66 km from Palmdale Regional Medical Center
The price is CA $175 per night
CA $175
CA $196 total
Jan 18 - Jan 19, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Valencia. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Six Flags Magic Mountain and Valencia Country Club are located nearby.

Hilton Garden Inn Valencia Six Flags
27710 The Old Rd Valencia CA
Free cancellation
Reserve now, pay when you stay
43.89 km from Palmdale Regional Medical Center
The price is CA $142 per night
CA $142
CA $159 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Valencia. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Six Flags Magic Mountain and Valencia Country Club are located nearby.

Ramada by Wyndham Burbank Airport
2900 N San Fernando Blvd Burbank CA
Free cancellation
Reserve now, pay when you stay
46 km from Palmdale Regional Medical Center
The price is CA $177 per night
CA $177
CA $196 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in Burbank. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the pool and the restaurant in our reviews. Popular attractions Universal Studios Hollywood and Warner Brothers Studio are located nearby.

Hotel Burbank
150 E Angeleno Ave Burbank CA
Free cancellation
Reserve now, pay when you stay
47.18 km from Palmdale Regional Medical Center
The price is CA $175 per night
CA $175
CA $195 total
Jan 12 - Jan 13, 2026
includes taxes & fees
Stay at this hotel in Burbank. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the pool and the restaurant in our reviews. Popular attractions Universal Studios Hollywood and Hollywood Walk of Fame are located nearby.
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About Palmdale Regional Medical Center Hotels Near Attractions
Do you have a full travel itinerary while visiting Palmdale Regional Medical Center? Don't waste your time commuting too far from Palmdale Regional Medical Center area attractions.
Palmdale Regional Medical Center hotels essential information
Accommodation | 1,283 hotels |
|---|---|
Lowest Price | CA $119 |
Highest Price | CA $233 |
Popular hotels | DoubleTree by Hilton Palmdale, CA, Holiday Inn Palmdale-Lancaster by IHG, Wyndham Garden Lancaster CA, Triplodge of Santa Clarita, Hotel Burbank, Ramada by Wyndham Burbank Airport, Travelodge by Wyndham Sylmar CA, Hotel Lexen - Newhall, Santa Clarita Motel, Hyatt Regency Valencia, Hilton Garden Inn Valencia Six Flags, Best Western Valencia/Six Flags Inn & Suites |
Recent Palmdale Regional Medical Center hotel reviews by fellow wanderers

Ramada by Wyndham Burbank Airport
5 out of 5
Posted 15 hours ago
Travelocity Verified Review
"Great staff very polite and "
A verified traveller stayed at Ramada by Wyndham Burbank Airport
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