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Hotels near Medical Center District

Hotel Valencia Riverwalk
150 E Houston St San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $124 per night from Jan 21 to Jan 22
CA $124
CA $186 total
Jan 21 - Jan 22, 2026
includes taxes & fees
Book a stay at this luxury hotel in San Antonio. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the ...
This place is absolutely gorgeous!
Reviewed on Dec 20, 2025

Drury Plaza Hotel San Antonio Riverwalk
105 S Saint Marys Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $164 per night from Jan 1 to Jan 2
CA $164
CA $194 total
Jan 1 - Jan 2, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in ...
Good place to stay
Reviewed on Dec 21, 2025

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
9700 West Military Drive San Antonio TX
Fully refundable
The price is CA $98 per night from Jan 11 to Jan 12
CA $98
CA $172 total
Jan 11 - Jan 12, 2026
includes taxes & fees
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and 2 hot tubs. Our guests praise the pool and the helpful staff in ...
Amazing property! Amenities. Clean space clean room. Love the pool area
Reviewed on Dec 22, 2025

Menger Hotel
204 Alamo Plaza San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $137 per night from Jan 4 to Jan 5
CA $137
CA $162 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this historic hotel in San Antonio. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the pool and the bar in our reviews. ...
Customer service was excellent. Love our stay definitely be back
Reviewed on Dec 21, 2025

Courtyard by Marriott Medical Center San Antonio
8585 Marriott Dr San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Dec 31 to Jan 1
CA $122
CA $144 total
Dec 31 - Jan 1, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
Excellent service and very clean rooms
Reviewed on Dec 15, 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
4431 Horizon Hill Blvd San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $122 per night from Dec 25 to Dec 26
CA $122
CA $144 total
Dec 25 - Dec 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
Great place to stay!
Reviewed on Dec 18, 2025

San Antonio Marriott Northwest Medical Center
3233 NW Loop 410 San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $135 per night from Jan 4 to Jan 5
CA $135
CA $161 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy a free area shuttle, room service, and a 24-hour fitness center. Our guests praise the helpful ...
Staff was very friendly. Room was clean, nice bar area with restaurant
Reviewed on Dec 21, 2025

Riverwalk Plaza
100 Villita Street San Antonio TX
Fully refundableReserve now, pay when you stay
Book a stay at this family-friendly hotel in San Antonio. Enjoy free WiFi, room service, and a 24-hour fitness center. Our guests praise the restaurant and the ...
Great staff and so convenient!
Reviewed on Dec 21, 2025

La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
303 Blum Street San Antonio TX
Fully refundableReserve now, pay when you stay
The price is CA $97 per night from Jan 4 to Jan 5
CA $97
CA $139 total
Jan 4 - Jan 5, 2026
includes taxes & fees
Book a stay at this business-friendly hotel in San Antonio. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the helpful ...
It was ok
Reviewed on Dec 22, 2025
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Recent Medical Center District hotel reviews by fellow wanderers

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Amazing property! Amenities. Clean space clean room. Love the pool area "
A verified traveller stayed at Hyatt Vacation Club at Wild Oak Ranch, San Antonio
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