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Featured San Mateo 4 Star hotels

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $184 per night from Apr 27 to Apr 28
CA $184
CA $273 total
Apr 27 - Apr 28
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,351 reviews)
Excellent

Reviewed on Apr 1, 2026

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $403 per night from Apr 5 to Apr 6
CA $403
CA $450 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
9.8/10 Exceptional! (1,540 reviews)
Wonderful breakfast! Restaurant on 4th floor- outstanding! The server actually took the time to make a few recommendations and it was not disappointing at all! A great one short stay at this hotel. Very convenient to the airport. By the way the cappuccino on 3rd floor was just top notch! I didn’t ...

Reviewed on Mar 29, 2026

Opens in a new windowGrand Hyatt at SFO
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

4 out of 5
835 Airport Blvd Burlingame CA
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Apr 5 to Apr 6
CA $145
CA $164 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8.6/10 Excellent! (1,497 reviews)
The only god thing about the hotel was the staff. They were exceptional.

Reviewed on Mar 29, 2026

Opens in a new windowDoubleTree by Hilton San Francisco Airport
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $149 per night from Apr 12 to Apr 13
CA $149
CA $175 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,567 reviews)
Very comfortable beds. Walls are pretty thin as we heard neighbors having basic conversations. Awesome location and wonderful employees. Would absolutely stay again.

Reviewed on Apr 1, 2026

Opens in a new windowHilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $150 per night from Apr 12 to Apr 13
CA $150
CA $176 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,028 reviews)
What a wonderful clean hotel with friendly staff and perfect location.

Reviewed on Mar 30, 2026

Opens in a new windowClub Quarters Hotel in San Francisco
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $277 per night from Apr 5 to Apr 6
CA $277
CA $390 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,143 reviews)
The hotel was very nice, and the staff was super kind

Reviewed on Mar 31, 2026

Opens in a new windowHyatt Regency San Francisco
Oakland Marriott City Center

Oakland Marriott City Center

4 out of 5
1001 Broadway Oakland CA
Fully refundableReserve now, pay when you stay
The price is CA $156 per night from Apr 12 to Apr 13
CA $156
CA $182 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this golf hotel in Oakland. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,005 reviews)
Parking was $51 which is ridiculous. I asked for a luggage cart and porter left to go get one and never returned so we had to carry our bins up to our room. Lastly, someone was smoking weed on our floor and it was aweful - the whole floor stunk. I would not stay here again

Reviewed on Mar 29, 2026

Opens in a new windowOakland Marriott City Center
Grand Hyatt San Francisco

Grand Hyatt San Francisco

4 out of 5
345 Stockton St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $212 per night from Apr 24 to Apr 25
CA $212
CA $315 total
Apr 24 - Apr 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
9/10 Wonderful! (1,013 reviews)
Clean. Nice rooms and property. Great location. Terrific breakfast.

Reviewed on Mar 31, 2026

Opens in a new windowGrand Hyatt San Francisco
Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4 out of 5
425 North Point San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $140 per night from Apr 26 to Apr 27
CA $140
CA $224 total
Apr 26 - Apr 27
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the restaurant and ...
9.2/10 Wonderful! (1,792 reviews)
Thank you

Reviewed on Apr 1, 2026

Opens in a new windowHotel Zoe Fisherman's Wharf
Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

4 out of 5
250 Beach Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $197 per night from Apr 29 to Apr 30
CA $197
CA $290 total
Apr 29 - Apr 30
includes taxes & fees
Book a stay at this boutique hotel in San Francisco. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the helpful staff ...
8.6/10 Excellent! (2,496 reviews)
Breakfast was good but doesnt include breakfast for kids which was a surprise not mentioned in the booking details. Room could be cleaner

Reviewed on Apr 1, 2026

Opens in a new windowHotel Zephyr San Francisco
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4 Star Hotels San Mateo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Mateo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Mateo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Mateo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Mateo hotel reviews by fellow wanderers

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