Find and compare 4 Star hotels in San Mateo

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Featured San Mateo 4 Star hotels

Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is CA $244 per night from Mar 6 to Mar 7
CA $244
CA $349 total
Mar 6 - Mar 7
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,069 reviews)
Clean, spacious room. Not good pressure in shower. Very slippery floor in shower and non-slip mat was very small.

Reviewed on Feb 2, 2026

Opens in a new windowHyatt Regency San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $167 per night from Mar 3 to Mar 4
CA $167
CA $252 total
Mar 3 - Mar 4
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
8.8/10 Excellent! (7,296 reviews)
Excellent! We highly recommend the Hotel.

Reviewed on Feb 13, 2026

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $172 per night from Feb 16 to Feb 17
CA $172
CA $203 total
Feb 16 - Feb 17
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (2,391 reviews)
Great

Reviewed on Feb 10, 2026

Opens in a new windowHilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
The price is CA $166 per night from Feb 15 to Feb 16
CA $166
CA $196 total
Feb 15 - Feb 16
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8.8/10 Excellent! (2,951 reviews)
Large spot on floor, wall dirty or scuffed up, very far from elevator for being an accessible room.

Reviewed on Feb 6, 2026

Opens in a new windowClub Quarters Hotel in San Francisco
InterContinental Mark Hopkins by IHG

InterContinental Mark Hopkins by IHG

4 out of 5
999 California Street San Francisco CA
Fully refundable
The price is CA $230 per night from Mar 14 to Mar 15
CA $230
CA $328 total
Mar 14 - Mar 15
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,322 reviews)
Incredible experience and lovely staff, we got in a bit early and they acocmodated us with earlym check in. The food at the restaurant was fresh and healthy meal options were available. The had daily free coffee until 1030 am which was also a nice touch. The location is also unbeatable right at the ...

Reviewed on Feb 7, 2026

Opens in a new windowInterContinental Mark Hopkins by IHG
Kimpton Alton Fisherman's Wharf by IHG

Kimpton Alton Fisherman's Wharf by IHG

4.5 out of 5
2700 JONES STREET San Francisco CA
Fully refundable
The price is CA $208 per night from Mar 1 to Mar 2
CA $208
CA $303 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9/10 Wonderful! (1,529 reviews)
Great room and very helpful staff

Reviewed on Feb 6, 2026

Opens in a new windowKimpton Alton Fisherman's Wharf by IHG
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $393 per night from Feb 28 to Mar 1
CA $393
CA $439 total
Feb 28 - Mar 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
9.6/10 Exceptional! (1,503 reviews)
Love, love, love the Grand Hyatt!!! From the cleanliness of the rooms, how quiet the rooms are, the food is great, excellent bar and an exceptional staff all around!!!! We just keep coming back.

Reviewed on Feb 11, 2026

Opens in a new windowGrand Hyatt at SFO
Oakland Marriott City Center

Oakland Marriott City Center

4 out of 5
1001 Broadway Oakland CA
Fully refundableReserve now, pay when you stay
The price is CA $152 per night from Mar 1 to Mar 2
CA $152
CA $178 total
Mar 1 - Mar 2
includes taxes & fees
Book a stay at this golf hotel in Oakland. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,006 reviews)
very comfortable, nice room. Staff was exceptional above and beyond the girl who answered the phone and checked us in.,Lupe, was above and beyond

Reviewed on Feb 9, 2026

Opens in a new windowOakland Marriott City Center
Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront

4 out of 5
600 Airport Boulevard Burlingame CA
Fully refundableReserve now, pay when you stay
The price is CA $155 per night from Mar 15 to Mar 16
CA $155
CA $176 total
Mar 15 - Mar 16
includes taxes & fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast ...
8.6/10 Excellent! (2,969 reviews)
Room was clean, price vs benefits, good deal.

Reviewed on Feb 12, 2026

Opens in a new windowHilton San Francisco Airport Bayfront
citizenM San Francisco Union Square

citizenM San Francisco Union Square

4 out of 5
72 Ellis Street San Francisco CA
The price is CA $165 per night from Feb 28 to Mar 1
CA $165
CA $194 total
Feb 28 - Mar 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the breakfast ...
9.4/10 Exceptional! (1,452 reviews)
Great

Reviewed on Feb 9, 2026

Opens in a new windowcitizenM San Francisco Union Square
Don't see what you're looking for?
See all available properties in San Mateo
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

4 Star Hotels San Mateo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Mateo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Mateo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Mateo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Mateo hotel reviews by fellow wanderers