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Featured San Mateo 4 Star hotels

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $189 per night from May 25 to May 26
CA $189
CA $279 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast ...
9/10 Wonderful! (7,470 reviews)
The room was clean but the bed was very firm. The bathtub wouldn’t drain after its first use but they did fix it the next day. The breakfast was incredible. The staff were cheerful and helpful. It was in easy walking distance of everything I wanted to do while in San Francisco. I did however only ...

Reviewed on May 17, 2026

Opens in a new windowHotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from May 25 to May 26
CA $158
CA $186 total
May 25 - May 26
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.8/10 Excellent! (2,773 reviews)
Great service. Wonderful room. Convenient location.

Reviewed on May 16, 2026

Opens in a new windowHilton San Francisco Financial District
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4 out of 5
424 Clay St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $174 per night from May 28 to May 29
CA $174
CA $205 total
May 28 - May 29
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9/10 Wonderful! (3,160 reviews)
Amenities were great and location was the best. The hotel staff were courteous and the coffee option in the lobby was the best. Everything about this hotel is a flying star.

Reviewed on May 14, 2026

Opens in a new windowClub Quarters Hotel in San Francisco
Oakland Marriott City Center

Oakland Marriott City Center

4 out of 5
1001 Broadway Oakland CA
Fully refundableReserve now, pay when you stay
The price is CA $154 per night from May 24 to May 25
CA $154
CA $179 total
May 24 - May 25
includes taxes & fees
Book a stay at this golf hotel in Oakland. Enjoy breakfast (surcharge), room service, and a 24-hour fitness center. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,015 reviews)
There was no breakfast, they were understaffed

Reviewed on May 16, 2026

Opens in a new windowOakland Marriott City Center
Grand Hyatt at SFO

Grand Hyatt at SFO

4 out of 5
55 S McDonnell Rd San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $425 per night from May 22 to May 23
CA $425
CA $475 total
May 22 - May 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the restaurant ...
9.8/10 Exceptional! (1,574 reviews)
Great and modern hotel. Easy to take AirTran to terminal.

Reviewed on May 16, 2026

Opens in a new windowGrand Hyatt at SFO
DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport

4 out of 5
835 Airport Blvd Burlingame CA
Fully refundableReserve now, pay when you stay
The price is CA $154 per night from May 30 to May 31
CA $154
CA $175 total
May 30 - May 31
includes taxes & fees
Book a stay at this business-friendly hotel in Burlingame. Enjoy breakfast (surcharge), a free airport shuttle, and room service. Our guests praise the helpful ...
8.8/10 Excellent! (1,555 reviews)
Clean, comfortable, updated, quiet, good bedding, nice decorations, everything worked, shuttle on time. Very happy with experience!

Reviewed on May 13, 2026

Opens in a new windowDoubleTree by Hilton San Francisco Airport
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $274 per night from May 21 to May 22
CA $274
CA $385 total
May 21 - May 22
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (2,226 reviews)
Nice

Reviewed on May 16, 2026

Opens in a new windowHyatt Regency San Francisco
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4 out of 5
275 S Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $169 per night from May 24 to May 25
CA $169
CA $200 total
May 24 - May 25
includes taxes & fees
Book a stay at this business-friendly hotel in South San Francisco. Enjoy free WiFi, a free airport shuttle, and a fitness center. Our guests praise the restaurant ...
8.4/10 Very Good! (2,293 reviews)
Promo was clean. Breakfast not goof

Reviewed on May 17, 2026

Opens in a new windowDoubleTree by Hilton San Francisco South Airport Blvd
Stanford Court San Francisco

Stanford Court San Francisco

4 out of 5
905 California Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $203 per night from May 25 to May 26
CA $203
CA $301 total
May 25 - May 26
includes taxes & fees
Book a stay at this luxury hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff ...
9/10 Wonderful! (1,393 reviews)
Good location for the cable car. Nice rooms and amenities. Plus staff was very friendly

Reviewed on May 16, 2026

Opens in a new windowStanford Court San Francisco
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $242 per night from Jun 7 to Jun 8
CA $242
CA $285 total
Jun 7 - Jun 8
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy 2 bars/lounges, breakfast (surcharge), and a 24-hour health club. Our guests praise the helpful ...
8.4/10 Very Good! (1,306 reviews)
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Reviewed on May 15, 2026

Opens in a new windowHilton San Francisco Union Square
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4 Star Hotels San Mateo

Looking to live it up on your vacation with a bit of luxury? Or maybe you’ve decided that your boss can afford to put you up at a place of your choice on your next business trip?

Come on, you deserve it!

The best part about staying in San Mateo 4 star hotels is that you’ll often be close to all the local sights and attractions. Whether you’re visiting the area for the first time or you’re back in town for more fun, a 4 star hotel is going to put you right in the heart of all the action.

Plus, you can rest easy knowing that you’re being well taken care of during your visit. Instead of worrying about where to eat or what to see, your friendly hotel staff will be happy to help you get whatever you need.

The best four star hotels in San Mateo will also frequently include access to high-quality fitness centers and pools, so you’ll feel like you’re staying in an exclusive resort rather than a hotel. You won’t have any excuse for not keeping up with your workout routine!

If you’re looking for 4 star hotels in San Mateo, you’ll find the most bang for your buck by booking your stay with Travelocity. Go explore a new city, and know you’re getting the best deal on a great hotel with the Travelocity Price Guarantee.

Recent San Mateo hotel reviews by fellow wanderers

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