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Hotels near Isle of Palms South

Hilton Jacksonville At Mayo Clinic
4745 Transformation Way Jacksonville FL
The price is CA $258 per night from Jan 24 to Jan 25
CA $258
CA $292 total
Jan 24 - Jan 25
includes taxes & fees
Book a stay at this luxury hotel in Jacksonville. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions St. Johns Town Center and TPC ...
Very clean
Reviewed on Dec 30, 2025

Margaritaville Jacksonville Beach
715 1st St N Jacksonville Beach FL
Fully refundableReserve now, pay when you stay
The price is CA $184 per night from Jan 4 to Jan 5
CA $184
CA $209 total
Jan 4 - Jan 5
includes taxes & fees
Book a stay at this beach hotel in Jacksonville Beach. Enjoy free WiFi, a beach locale, and breakfast (surcharge). Our guests praise the pool and the helpful ...
Everything was amazing!!!
Reviewed on Dec 28, 2025

Hyatt Regency Jacksonville
225 E Coastline Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $222 per night from Jan 31 to Feb 1
CA $222
CA $255 total
Jan 31 - Feb 1
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...
Am convinced
Reviewed on Dec 28, 2025

Embassy Suites by Hilton Jacksonville Baymeadows
9300 Baymeadows Road Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $179 per night from Feb 1 to Feb 2
CA $179
CA $203 total
Feb 1 - Feb 2
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, room service, and a 24-hour fitness center. Our guests praise the breakfast ...
We had an excellent stay at the Embassy Suites. The rooms were spotless and very well maintained, and the hotel overall was impressively clean from top to bottom. One of the highlights was the breakfast, which truly exceeded expectations. There was a full omelette station along with pancakes, sausages, ...
Reviewed on Dec 27, 2025

San Marco Inn East
3558 Phillips Hwy Jacksonville FL
Fully refundableReserve now, pay when you stay
Stay at this motel in Jacksonville. Enjoy free WiFi, free parking, and 24-hour room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
Very clean
Reviewed on Dec 28, 2025

The Villas of Amelia Island
8 Amelia Village Circle, Amelia Island Fernandina Beach FL
Fully refundableReserve now, pay when you stay
The price is CA $218 per night from Jan 5 to Jan 6
CA $218
CA $306 total
Jan 5 - Jan 6
includes taxes & fees
Book a stay at this beach vacation home in Fernandina Beach. Enjoy free WiFi, 2 outdoor pools, and a full-service spa. Our guests praise the helpful staff in ...
Clean room, beautiful view, responsive staff.
Reviewed on Dec 26, 2025

Comfort Suites Baymeadows Near Butler Blvd
8277 Western Way Cir Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $145 per night from Jan 12 to Jan 13
CA $145
CA $164 total
Jan 12 - Jan 13
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
The room was comfortable. Breakfast was good.
Reviewed on Dec 30, 2025

Southbank Hotel by Marriott Jacksonville Riverwalk
1515 Prudential Dr Jacksonville FL
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Jan 21 to Jan 22
CA $147
CA $167 total
Jan 21 - Jan 22
includes taxes & fees
Book a stay at this business-friendly hotel in Jacksonville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
Always a great stay
Reviewed on Dec 30, 2025

DoubleTree by Hilton Hotel Jacksonville Riverfront
1201 Riverplace Boulevard Jacksonville FL
The price is CA $174 per night from Jan 3 to Jan 4
CA $174
CA $197 total
Jan 3 - Jan 4
includes taxes & fees
Stay at this hotel in Jacksonville. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the helpful staff in our reviews. Popular ...
The outside was very nice and the staff was great
Reviewed on Dec 27, 2025
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Recent Isle of Palms South hotel reviews by fellow wanderers

Hilton Jacksonville At Mayo Clinic
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Very clean"
A verified traveller stayed at Hilton Jacksonville At Mayo Clinic
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