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Hotels near Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct, San Diego, CA
Free cancellation
3.15 km from Otay Mesa
The price is CA $168 per night
CA $168
CA $191 total
Aug 14 - Aug 15
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions Macroplaza Insurgentes and North Island Credit Union Amphitheatre are located nearby.
Pool
Breakfast included

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free cancellation
Reserve now, pay when you stay
25.71 km from Otay Mesa
The price is CA $209 per night
CA $209
CA $282 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and USS Midway Museum are located nearby.
Pool
Free airport shuttle

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free cancellation
Reserve now, pay when you stay
24.77 km from Otay Mesa
The price is CA $234 per night
CA $234
CA $346 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Hot tub

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
33.74 km from Otay Mesa
The price is CA $228 per night
CA $228
CA $262 total
Aug 18 - Aug 19
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Pool
Hot tub

Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
33.92 km from Otay Mesa
The price is CA $228 per night
CA $228
CA $329 total
Aug 26 - Aug 27
includes taxes & fees
Stay at this 4-star spa hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Mission Beach and Mission Bay are located nearby.
Pool
Hot tub

Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy, San Diego, CA
Free cancellation
Reserve now, pay when you stay
25.03 km from Otay Mesa
The price is CA $244 per night
CA $244
CA $321 total
Aug 17 - Aug 18
includes taxes & fees
Book a stay at this family-friendly hotel in San Diego. Enjoy free breakfast, room service, and a fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions USS Midway Museum and Port of San Diego are located nearby.
Pool
Breakfast included

Dextro, Little Italy, BW Premier Collection
1617 1st Avenue, San Diego, CA
Free cancellation
Reserve now, pay when you stay
25.38 km from Otay Mesa
The price is CA $153 per night
CA $153
CA $177 total
Sep 1 - Sep 2
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful staff and the clean rooms in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Free WiFi

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Free cancellation
Reserve now, pay when you stay
29.09 km from Otay Mesa
The price is CA $162 per night
CA $162
CA $187 total
Aug 17 - Aug 18
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Pool
Hot tub

Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free cancellation
Reserve now, pay when you stay
23.7 km from Otay Mesa
The price is CA $244 per night
CA $244
CA $349 total
Aug 14 - Aug 15
includes taxes & fees
Stay at this 4-star spa hotel in San Diego. Enjoy a full-service spa, 2 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Pool
Hot tub

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
24.49 km from Otay Mesa
The price is CA $300 per night
CA $300
CA $409 total
Sep 1 - Sep 2
includes taxes & fees
Book a stay at this spa hotel in San Diego. Enjoy 2 outdoor pools, a full-service spa, and 5 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions Petco Park and Port of San Diego are located nearby.
Pool
Hot tub

Hampton Inn San Diego/Mission Valley
2151 Hotel Circle South, San Diego, CA
Free cancellation
Reserve now, pay when you stay
29.56 km from Otay Mesa
The price is CA $186 per night
CA $186
CA $213 total
Aug 10 - Aug 11
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions San Diego Zoo and Balboa Park are located nearby.
Pool
Breakfast included

Sheraton San Diego Resort
1380 Harbor Island Dr, San Diego, CA
Free cancellation
Reserve now, pay when you stay
28.09 km from Otay Mesa
The price is CA $162 per night
CA $162
CA $243 total
Aug 31 - Sep 1
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant in our reviews. Popular attractions Port of San Diego and Petco Park are located nearby.
Pool
Hot tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Otay Mesa Hotels
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Otay Mesa hotels essential information
Accommodation | 4,639 hotels |
---|---|
Lowest Price | CA $153 |
Highest Price | CA $300 |
Popular hotels | Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG, Wyndham San Diego Bayside, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Hyatt Regency Mission Bay Spa and Marina, Embassy Suites by Hilton San Diego Bay Downtown, Dextro, Little Italy, BW Premier Collection, Handlery Hotel, Hilton San Diego Bayfront, Marriott Marquis San Diego Marina, Hampton Inn San Diego/Mission Valley, Sheraton San Diego Resort |
Recent Otay Mesa hotel reviews by fellow wanderers

Marriott Marquis San Diego Marina
5 out of 5
Posted 2 days ago
Travelocity Verified Review
"Great location great restaurants and fun/entertainment within walking distance."
A verified traveller from Santa Ana stayed at Marriott Marquis San Diego Marina
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