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Hotels near Otay Mesa
Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $221 per night from Aug 31 to Sep 1
CA $221
CA $254 total
Aug 31 - Sep 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant in ...
"Qué está muy cerca del mar?"
Reviewed on Aug 15, 2026
Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $258 per night from Aug 28 to Aug 29
CA $258
CA $375 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the pool and the ...
"Great experience, very convenient location for all the things"
Reviewed on Aug 16, 2026
The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $262 per night from Aug 30 to Aug 31
CA $262
CA $341 total
Aug 30 - Aug 31
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
"Our room was ok clean. The bed was really hard and there was a gap underneath the door. The housekeeping was washing the walkway and when we entered the room the carpet was soaking wet. The tall tropical plants look unkept. We did enjoy the pool areas. It was an overall ok stay . The surrounding ..."
Reviewed on Aug 15, 2026
Hard Rock Hotel San Diego
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $246 per night from Aug 24 to Aug 25
CA $246
CA $352 total
Aug 24 - Aug 25
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
"Very nice stay and clean. The only bad thing I have to say is paying 70 dollars for Valet which was secure parking but they parked my truck under a dripping water line. .I'm very upset ,now I have water spots on windshield and hood."
Reviewed on Aug 16, 2026
Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $211 per night from Aug 24 to Aug 25
CA $211
CA $293 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
"Needs new carpeting in the lobby tripped a couple of times because the carpeting is loose and has rolls in it."
Reviewed on Aug 16, 2026
Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $200 per night from Aug 23 to Aug 24
CA $200
CA $300 total
Aug 23 - Aug 24
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
"Great overall stay with awesome amenities"
Reviewed on Aug 15, 2026
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2296 Niels Bohr Ct San Diego CA
Fully refundable
The price is CA $193 per night from Aug 17 to Aug 18
CA $193
CA $219 total
Aug 17 - Aug 18
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
"Pool was nice room was clean breakfast was a bit bland tho"
Reviewed on Aug 15, 2026
Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $310 per night from Sep 7 to Sep 8
CA $310
CA $429 total
Sep 7 - Sep 8
includes taxes & fees
Book a stay at this beach resort in San Diego. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in ...
Omni San Diego Hotel at the Ballpark
675 L St San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $210 per night from Aug 31 to Sep 1
CA $210
CA $306 total
Aug 31 - Sep 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
About Otay Mesa Hotels
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Recent Otay Mesa hotel reviews by fellow wanderers
Hard Rock Hotel San Diego
4 out of 5
Posted 1 hour ago
Travelocity Verified Review
"Very nice stay and clean. The only bad thing I have to say is paying 70 dollars for Valet which was secure parking but they parked my truck under a dripping water line. .I'm very upset ,now I have water spots on windshield and hood."
A verified traveller stayed at Hard Rock Hotel San Diego
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