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Featured Mestre 5 Star hotels

The St. Regis Venice

The St. Regis Venice

5 out of 5
Campo Barozzi Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,238 per night from Nov 25 to Nov 26
CA $1,238
CA $1,378 total
Nov 25 - Nov 26
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, 2 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (156 reviews)
"The St. Regis was a dream. Our room was right over the Grand Canal with a direct view of the Basilica Santa Maria della Salute. All the amenities were exquisite. It felt like having an apartment in Venice. Their famous restaurant Gio’s was incredible and we loved the Arts Bar where they have art ..."

Reviewed on Nov 8, 2026

Opens in a new windowThe St. Regis Venice
Hilton Molino Stucky Venice

Hilton Molino Stucky Venice

5 out of 5
Isola Della Giudecca 810 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $269 per night from Dec 6 to Dec 7
CA $269
CA $312 total
Dec 6 - Dec 7
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy an outdoor pool, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff in ...
Opens in a new windowHilton Molino Stucky Venice
Baglioni Hotel Luna - The Leading Hotels of the World

Baglioni Hotel Luna - The Leading Hotels of the World

5 out of 5
San Marco, 1243 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $665 per night from Dec 1 to Dec 2
CA $665
CA $747 total
Dec 1 - Dec 2
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.4/10 Exceptional! (1,003 reviews)
"Historical and classic. Well kept and incredibly close to major sites. My bias is I prefer more modern hotel furnishings. Felt like I was in a museum but still comfy"

Reviewed on Nov 5, 2026

Opens in a new windowBaglioni Hotel Luna - The Leading Hotels of the World
Nolinski Venezia - Evok Collection

Nolinski Venezia - Evok Collection

5 out of 5
2032 Calle Larga XXII Marzo Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $775 per night from Dec 7 to Dec 8
CA $775
CA $869 total
Dec 7 - Dec 8
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a full-service spa, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. Popular ...
Opens in a new windowNolinski Venezia - Evok Collection
The Venice Venice Hotel

The Venice Venice Hotel

5 out of 5
Sestiere Cannaregio 5631 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $1,044 per night from Nov 27 to Nov 28
CA $1,044
CA $1,165 total
Nov 27 - Nov 28
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a 24-hour fitness center, and onsite spa services. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowThe Venice Venice Hotel
Cà Bonfadini Historic Experience

Cà Bonfadini Historic Experience

5 out of 5
Fondamenta Savorgan 462 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $459 per night from Dec 10 to Dec 11
CA $459
CA $521 total
Dec 10 - Dec 11
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff in our reviews. ...
Opens in a new windowCà Bonfadini Historic Experience
Radisson Collection Hotel, Palazzo Nani Venice

Radisson Collection Hotel, Palazzo Nani Venice

5 out of 5
Fondamenta Cannaregio 1105 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $462 per night from Nov 24 to Nov 25
CA $462
CA $524 total
Nov 24 - Nov 25
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy breakfast (surcharge), a fitness center, and a 24-hour front desk. Our guests praise the helpful staff in our ...
9.8/10 Exceptional! (214 reviews)
"The Hotel was clean and staff very friendly. The hotel was in a great location. Lose to a water taxi and close to many restaurants and shopping. Safe area at night even when paths are less populated. The room had a complimentary bottle of wine and several Complimentary waters. Complimentary breakfast ..."

Reviewed on Oct 27, 2026

Opens in a new windowRadisson Collection Hotel, Palazzo Nani Venice
Palazzo Venart Luxury Hotel

Palazzo Venart Luxury Hotel

5 out of 5
Santa Croce 1961 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $735 per night from Nov 17 to Nov 18
CA $735
CA $824 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, a 24-hour front desk, and an area shuttle (surcharge). Popular attractions Piazzale Roma and St. ...
9.8/10 Exceptional! (197 reviews)
"If you want understated luxury this is the hotel for you."

Reviewed on Oct 28, 2026

Opens in a new windowPalazzo Venart Luxury Hotel
Violino D’Oro Venezia

Violino D’Oro Venezia

5 out of 5
San Marco 2091 Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $857 per night from Nov 17 to Nov 18
CA $857
CA $958 total
Nov 17 - Nov 18
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free breakfast, free WiFi, and 24-hour room service. Popular attractions St. Mark's Square and Piazzale Roma ...
Opens in a new windowViolino D’Oro Venezia
Hotel Nani Mocenigo Palace

Hotel Nani Mocenigo Palace

5 out of 5
960 Fondamenta Nani Venice VE
Fully refundableReserve now, pay when you stay
The price is CA $304 per night from Nov 24 to Nov 25
CA $304
CA $350 total
Nov 24 - Nov 25
includes taxes & fees
Book a stay at this luxury hotel in Venice. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the property condition ...
Opens in a new windowHotel Nani Mocenigo Palace
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Mestre

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Mestre to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mestre 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Mestre before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

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