Find and compare 5 Star hotels in Mestre
Wander Wisely with exceptional service, 24/7 support
Save an extra 10% or more on select hotels with Member Discounts
Access exclusive hotel deals, only with the Travelocity app
Check prices for these dates
Featured Mestre 5 Star hotels

The St. Regis Venice
"The St. Regis was a dream. Our room was right over the Grand Canal with a direct view of the Basilica Santa Maria della Salute. All the amenities were exquisite. It felt like having an apartment in Venice. Their famous restaurant Gio’s was incredible and we loved the Arts Bar where they have art ..."
Reviewed on Nov 8, 2026

Hilton Molino Stucky Venice

Baglioni Hotel Luna - The Leading Hotels of the World
"Historical and classic. Well kept and incredibly close to major sites. My bias is I prefer more modern hotel furnishings. Felt like I was in a museum but still comfy"
Reviewed on Nov 5, 2026

Nolinski Venezia - Evok Collection

The Venice Venice Hotel

Cà Bonfadini Historic Experience

Radisson Collection Hotel, Palazzo Nani Venice
"The Hotel was clean and staff very friendly. The hotel was in a great location. Lose to a water taxi and close to many restaurants and shopping. Safe area at night even when paths are less populated. The room had a complimentary bottle of wine and several Complimentary waters. Complimentary breakfast ..."
Reviewed on Oct 27, 2026

Palazzo Venart Luxury Hotel
"If you want understated luxury this is the hotel for you."
Reviewed on Oct 28, 2026

Violino D’Oro Venezia

Hotel Nani Mocenigo Palace
Five Star Hotels in Mestre
Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Mestre to make sure your trip is as extravagantly comfortable as you expect.
Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!
Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.
For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Mestre 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.
Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Mestre before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.
Recent Mestre hotel reviews by fellow wanderers

Best Western Plus Hotel Bologna
"Comfortable bed, big room, good lovation"
Explore More Ways to Travel with Travelocity
- 5 Star Hotels in San Marco
- Cannaregio Hotels
- Casier Hotels
- Cavallino-Treporti Hotels
- All Inclusive Resorts & in Veneto
- Veneto Hotels
- Dolo Hotels
- Isola delle Rose Hotels
- Hotels near Marco Polo
- Marcon Hotels
- B&B in Mestre
- Condos in Mestre
- Hostels in Mestre
- Cheap Hotels in Mestre
- Gay Friendly Hotels in Mestre
- Mestre Hotels
- Mira Hotels
- Mogliano Veneto Hotels
- Oriago Hotels
- Punta Sabbioni Hotels
- Hotels near Rialto Bridge
- San Clemente Hotels
- San Clemente Hotels
- Hotels near San Giorgio Maggiore
- Cheap Hotels in San Marco
- San Polo Hotels
- Santa Croce Hotels
- Hotels near St. Mark's Basilica
- Hotels near St. Mark's Square
- Torcello Hotels
- Condos in Veneto
- Hostels in Veneto
- Farmstay in Venice
- Venice City Center Hotels
- Cottages in Venice
- Golf Resorts & in Venice
- Venice Hotels
- Houseboat Rentals in Venice
- Flights to Mira
- Flights to Riviera del Brenta
- Flights to Venice
- Air Canada Toronto (YYZ) to Venice (VCE) flights
- Delta New York (JFK) to Venice (VCE) flights
- Leav Aviation Paris (CDG) to Venice (VCE) flights
- Lufthansa Frankfurt (FRA) to Venice (VCE) flights
- Lufthansa Toronto (YYZ) to Venice (VCE) flights
- Norwegian Air Sweden Copenhagen (CPH) to Venice (VCE) flights
- Westjet Calgary (YYC) to Venice (VCE) flights
- Flights from Athens to Mestre
- Flights from Paris (CDG) to Venice (VCE)
- Flights from Doncaster (DSA) to Treviso (TSF)
- Flights from Florianópolis (FLN) to Treviso (TSF)
- Flights from Spokane (GEG) to Treviso (TSF)
- Flights from Glasgow (PIK) to Treviso (TSF)
- Flights from Seattle (SEA) to Venice (VCE)
- Flights from Thessaloniki (SKG) to Treviso (TSF)
- Flights from Comox (YQQ) to Venice (VCE)
- Flights from Vancouver (YVR) to Venice (VCE)
- Flights from Toronto (YYZ) to Treviso (TSF)
- Flights from Toronto (YYZ) to Venice (VCE)
- Ace Rental Cars in San Marco
- Ada Rental Cars in San Marco
- Airport Van Rental Rental Cars in Mestre
- Auto Rent Rental Cars in Mestre
- Avis Rental Cars in Marco Polo
- Avis Rental Cars in San Marco
- Budget Rental Cars in Mestre
- Car rentals near Bartolomeo Colleoni Monument
- Rental cars Marco Polo airport
- Car rental Mestre
- Car rental Mira
- Car rental Punta Sabbioni
- Car rentals near Venice
- Compact Car Rentals in Mestre
- Dirent Rental Cars in Marco Polo
- Dollar Rent A Car Rental Cars in San Marco
- Firefly Rental Cars in Mestre
- Full-Size Car Rentals in Mestre
- Hertz Rental Cars in San Marco
- Keddy By Europcar Rental Cars in Marco Polo
- Luxury Car Rentals in San Marco
- Mini Car Rentals in San Marco
- Minivan Car Rentals in Venice
- National Car Rental Rental Cars in Marco Polo
- Payless Rental Cars in Marco Polo
- Pickup Car Rentals in San Marco
- Sixt Rental Cars in San Marco
- Sports Car Car Rentals in Mestre
- Top Rent a Car Rental Cars in Marco Polo




