Find and compare 5 Star hotels in Brookline

Name: Mandarin Oriental, Boston
Price range: CA $768
Rating: 9.4

Wander Wisely with exceptional service, 24/7 support

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Featured Brookline 5 Star hotels

The Langham, Boston

250 Franklin St Boston MA

CA $717

CA $835 total

Jul 19 - Jul 20

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...

9.8/10 Exceptional! (1,003 reviews)

"No restaurant on site for evening meals"

Reviewed on Jun 27, 2026

Omni Boston Hotel at the Seaport

450 Summer Street Boston MA

Fully refundableReserve now, pay when you stay

CA $328

CA $440 total

Jul 6 - Jul 7

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the breakfast and the pool in our reviews. ...

9.2/10 Wonderful! (4,729 reviews)

"The staff were incredibly friendly and helpful in finding local sights and food. The room was lovely. We were able to check in early and were also given an upgrade to our room. I would recommend staying at this hotel and look forward to returning in the future."

Reviewed on Jun 27, 2026

Encore Boston Harbor

1 Broadway Everett MA

Fully refundableReserve now, pay when you stay

CA $325

CA $363 total

Jul 19 - Jul 20

includes taxes & fees

Book a stay at this luxury hotel in Everett. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean rooms in ...

9.6/10 Exceptional! (3,874 reviews)

"Very nice"

Reviewed on Jun 28, 2026

The Newbury Boston

15 Arlington St Boston MA

Fully refundableReserve now, pay when you stay

CA $850

CA $1,064 total

Jul 1 - Jul 2

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful staff ...

9.4/10 Exceptional! (669 reviews)

"The Newbury Boston horel was absolutely amazing, beautiful, and clean. Staff were very friendly and helpful. It is located at a very prestigious area right across the street from the garden and where all the designer boutiques are. Will definitely return to this property"

Reviewed on Jun 27, 2026

Boston Harbor Hotel

70 Rowes Wharf Boston MA

CA $792

CA $922 total

Jul 6 - Jul 7

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the helpful staff and the room service in ...

9.8/10 Exceptional! (1,001 reviews)

"We were there for 5 days. It was impeccable. The location, service, ambiance everything was perfect! All small attentions that makes you feel comfortable. We took the water taxi from (and to) the airport directly to the hotel fastest way to get there. Easy to walk around and along the waterfront. ..."

Reviewed on Jun 15, 2026

The Liberty, a Marriott Luxury Collection Hotel, Boston

215 Charles St Boston MA

CA $353

CA $453 total

Jul 1 - Jul 2

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, 2 restaurants, and 4 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.8/10 Excellent! (1,005 reviews)

"Great hotel- cool vibe."

Reviewed on Jun 27, 2026

InterContinental Boston by IHG

510 Atlantic Ave Boston MA

CA $324

CA $441 total

Jul 5 - Jul 6

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy a full-service spa, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (1,150 reviews)

"Hotel was beautiful and well maintained. The staff were very friendly and accommodating. I enjoyed my stay. The hotel fees/parking were on the higher end."

Reviewed on Jun 27, 2026

Four Seasons Hotel One Dalton Street, Boston

One Dalton Street Boston MA

CA $894

CA $1,041 total

Jul 6 - Jul 7

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...

9.6/10 Exceptional! (420 reviews)

"Beautiful and everything that you would expect from the Four Seasons."

Reviewed on Jun 22, 2026

Four Seasons Hotel Boston

200 Boylston St Boston MA

CA $1,171

CA $1,364 total

Jul 26 - Jul 27

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the room service ...

9.4/10 Exceptional! (474 reviews)

"perfecto"

Reviewed on Jun 8, 2026

Mandarin Oriental, Boston

776 Boylston St Boston MA

Fully refundableReserve now, pay when you stay

CA $768

CA $894 total

Jul 26 - Jul 27

includes taxes & fees

Book a stay at this luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff and the room ...

9.4/10 Exceptional! (431 reviews)

"Very central"

Reviewed on Jun 24, 2026

Don't see what you're looking for?

See all available properties in Brookline

View all properties

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Brookline

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Brookline to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Brookline 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Brookline before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.