Find and compare 5 Star hotels in Brookline

Start date: Check-in selected.
To Date
End date: Check-out

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

Featured Brookline 5 Star hotels

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport

5 out of 5
450 Summer Street, Boston, MA
Fully refundableReserve now, pay when you stay
The price is CA $251 per night from Nov 9 to Nov 10
CA $251
CA $350 total
Nov 9 - Nov 10
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 4 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,151 reviews)
"wonderful"

Reviewed on Oct 16, 2025

Opens in a new windowOmni Boston Hotel at the Seaport
Encore Boston Harbor

Encore Boston Harbor

5 out of 5
1 Broadway, Everett, MA
Fully refundableReserve now, pay when you stay
The price is CA $382 per night from Nov 16 to Nov 17
CA $382
CA $427 total
Nov 16 - Nov 17
includes taxes & fees
Stay at this 5-star luxury hotel in Everett. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean rooms in ...
9.6/10 Exceptional! (3,346 reviews)
Excellent stay
"Modern, spacious and immaculate room. View on the harbor was beautiful. Rare Steakhouse was wonderful. Meat was excellent and so was the service."

Reviewed on Oct 19, 2025

Opens in a new windowEncore Boston Harbor
The Newbury Boston

The Newbury Boston

5 out of 5
15 Arlington St, Boston, MA
Fully refundableReserve now, pay when you stay
The price is CA $817 per night from Nov 16 to Nov 17
CA $817
CA $1,024 total
Nov 16 - Nov 17
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful staff ...
9.2/10 Wonderful! (523 reviews)
"Great location, very large room for a city hotel, not the most lavish or current decor but I would definitely stay here again. Liked this more than the Raffles."

Reviewed on Oct 14, 2025

Opens in a new windowThe Newbury Boston
The Langham, Boston

The Langham, Boston

5 out of 5
250 Franklin St, Boston, MA
Fully refundableReserve now, pay when you stay
The price is CA $638 per night from Nov 7 to Nov 8
CA $638
CA $743 total
Nov 7 - Nov 8
includes taxes & fees
Book a stay at this luxury hotel in Boston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.6/10 Exceptional! (1,013 reviews)
"I would never stay any where else. Absolutely amazing."

Reviewed on Oct 20, 2025

Opens in a new windowThe Langham, Boston
Four Seasons Hotel Boston

Four Seasons Hotel Boston

5 out of 5
200 Boylston St, Boston, MA
The price is CA $1,325 per night from Nov 9 to Nov 10
CA $1,325
CA $1,543 total
Nov 9 - Nov 10
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the room service ...
9.2/10 Wonderful! (443 reviews)
"The Vault is so genius. The staff is beyond compare, intelligent, professional to the highest standard and very thoughtful."

Reviewed on Sep 24, 2025

Opens in a new windowFour Seasons Hotel Boston
Boston Harbor Hotel

Boston Harbor Hotel

5 out of 5
70 Rowes Wharf, Boston, MA
Fully refundableReserve now, pay when you stay
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, a marina, and breakfast (surcharge). Our guests praise the helpful staff and the room service in ...
9.6/10 Exceptional! (1,019 reviews)
"Great location, staff all great, bars and restaurants good, upgraded room was perfect"

Reviewed on Oct 11, 2025

Opens in a new windowBoston Harbor Hotel
InterContinental Boston by IHG

InterContinental Boston by IHG

5 out of 5
510 Atlantic Ave, Boston, MA
Fully refundable
The price is CA $335 per night from Oct 30 to Oct 31
CA $335
CA $454 total
Oct 30 - Oct 31
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy a full-service spa, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,012 reviews)
"amzing"

Reviewed on Oct 15, 2025

Opens in a new windowInterContinental Boston by IHG
The Liberty, a Marriott Luxury Collection Hotel, Boston

The Liberty, a Marriott Luxury Collection Hotel, Boston

5 out of 5
215 Charles St, Boston, MA
Fully refundableReserve now, pay when you stay
The price is CA $416 per night from Nov 16 to Nov 17
CA $416
CA $519 total
Nov 16 - Nov 17
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, 2 restaurants, and 4 bars/lounges. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.6/10 Excellent! (1,012 reviews)
"Great Location!"

Reviewed on Oct 16, 2025

Opens in a new windowThe Liberty, a Marriott Luxury Collection Hotel, Boston
The Ritz-Carlton, Boston

The Ritz-Carlton, Boston

5 out of 5
10 Avery St, Boston, MA
Fully refundableReserve now, pay when you stay
The price is CA $1,044 per night from Nov 9 to Nov 10
CA $1,044
CA $1,216 total
Nov 9 - Nov 10
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy breakfast (surcharge), 24-hour room service, and a health club. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (400 reviews)
"Lovely property, not as “Ritzy” as other RC but decent, the staff is definitely top notch all around."

Reviewed on Oct 3, 2025

Opens in a new windowThe Ritz-Carlton, Boston
Four Seasons Hotel One Dalton Street, Boston

Four Seasons Hotel One Dalton Street, Boston

5 out of 5
One Dalton Street, Boston, MA
Fully refundableReserve now, pay when you stay
The price is CA $953 per night from Nov 18 to Nov 19
CA $953
CA $1,110 total
Nov 18 - Nov 19
includes taxes & fees
Stay at this 5-star luxury hotel in Boston. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9.6/10 Exceptional! (356 reviews)
"wonderful stay ...Love the staff ...doormen, valet and front desk all super friendly and helpful :)"

Reviewed on Oct 13, 2025

Opens in a new windowFour Seasons Hotel One Dalton Street, Boston
Don't see what you're looking for?
See all available properties in Brookline
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Five Star Hotels in Brookline

Looking for your own little slice of heaven during your next trip? Check out all the best 5 star hotels in Brookline to make sure your trip is as extravagantly comfortable as you expect.

Whether you plan on staying in your room the whole time or getting out and enjoying the city, you’ll be living the life while staying at your luxury accommodation. With so many amenities at your beck and call, you might try to turn your stay into a staycation!

Many of the five star hotels have award-winning restaurants you can dine at, as well as plush bedding and a concierge service to take care of your every need. Most also offer pools and modern fitness centers, not to mention high-speed Wi-Fi.

For your next trip, book a hotel that can be your own little hideaway, whether you’re in town for business or leisure. Brookline 5 star hotels provide you with all the comforts and amenities you expect from a sophisticated hotel, with a staff that’s happy to ensure you have everything you need to feel at home.

Whether you’re a first-time guest, or you’ve stayed in 5 star hotels in Brookline before, you’ll have no shortage of options to choose from on your next trip when you book with Travelocity. Browse our vast selection and find great deals on luxury lodging.

Recent Brookline hotel reviews by fellow wanderers