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Hotels near Otay Mesa West

Pendry San Diego

Pendry San Diego

5 out of 5
550 J Street San Diego CA
The price is CA $451 per night from Jan 22 to Jan 23
CA $451
CA $596 total
Jan 22 - Jan 23
includes taxes & fees
Book a stay at this luxury hotel in San Diego. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the helpful staff and the clean rooms ...
Well decorated, super clean high touches

Reviewed on Jan 17, 2026

Opens in a new windowPendry San Diego
The US Grant, a Luxury Collection Hotel, San Diego

The US Grant, a Luxury Collection Hotel, San Diego

5 out of 5
326 Broadway San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $420 per night from Feb 16 to Feb 17
CA $420
CA $488 total
Feb 16 - Feb 17
includes taxes & fees
Book a stay at this luxury hotel in San Diego. Enjoy breakfast (surcharge), 24-hour room service, and a 24-hour fitness center. Our guests praise the helpful ...
Good

Reviewed on Jan 3, 2026

Opens in a new windowThe US Grant, a Luxury Collection Hotel, San Diego
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $276 per night from Jan 22 to Jan 23
CA $276
CA $396 total
Jan 22 - Jan 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the helpful staff ...
Great location and cleanliness of room and overall hotel amenities.

Reviewed on Jan 18, 2026

Opens in a new windowManchester Grand Hyatt San Diego
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $659 per night from Feb 3 to Feb 4
CA $659
CA $831 total
Feb 3 - Feb 4
includes taxes & fees
Stay at this hotel in San Diego. Enjoy free WiFi, 2 restaurants, and a nightclub. Our guests praise the helpful staff and the convenient parking in our reviews. ...
Clean room

Reviewed on Jan 20, 2026

Opens in a new windowHard Rock Hotel San Diego
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4 out of 5
1646 Front St San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $234 per night from Jan 31 to Feb 1
CA $234
CA $272 total
Jan 31 - Feb 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Nice room. Great location

Reviewed on Jan 20, 2026

Opens in a new windowCourtyard by Marriott San Diego Downtown Little Italy
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $221 per night from Jan 22 to Jan 23
CA $221
CA $285 total
Jan 22 - Jan 23
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina, and 2 hot tubs. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
Easy check-in, free room upgrade, clean room, nice amenities and beautiful hotel grounds.

Reviewed on Jan 20, 2026

Opens in a new windowThe Dana on Mission Bay
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $158 per night from Jan 22 to Jan 23
CA $158
CA $183 total
Jan 22 - Jan 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
Clean room. Great views, great staff

Reviewed on Jan 15, 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $276 per night from Jan 22 to Jan 23
CA $276
CA $378 total
Jan 22 - Jan 23
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, 3 outdoor pools, and 5 restaurants. Our guests praise the pool and the restaurant ...
I love that place !!! I will definitely come back again.

Reviewed on Jan 18, 2026

Opens in a new windowSheraton San Diego Resort
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4 out of 5
901 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
The price is CA $170 per night from Jan 31 to Feb 1
CA $170
CA $195 total
Jan 31 - Feb 1
includes taxes & fees
Book a stay at this business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
Room was clean, Hotel was in a great location to areas we wanted to visit, staff was courteous and was able to resolve issues with gate quickly

Reviewed on Jan 14, 2026

Opens in a new windowHilton San Diego Mission Valley
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