The St. Regis Toronto offers 258 air-conditioned accommodations, which are accessible via exterior corridors and feature iPod docking stations and MP3 docking stations. Each accommodation is individually furnished and decorated. Pillowtop beds feature Egyptian cotton sheets, down comforters, and premium bedding. A pillow menu is available. 42-inch LCD televisions come with premium digital channels and pay movies. Bathrooms include separate bathtubs and showers, bathrobes, slippers, and complimentary toiletries.
In-room wireless Internet access is available for a surcharge. Business-friendly amenities include desks and complimentary newspapers, as well as phones; free local calls are provided (restrictions may apply). Additionally, rooms include laptop-compatible safes and espresso makers. In-room massages and hypo-allergenic bedding can be requested. A nightly turndown service is provided and housekeeping is offered daily. Renovation of all guestrooms was completed in January 2020.