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Serenity South -- Gardens, River-Views, and Refreshing Space

Cape Girardeau vacation home with kitchen

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Photo gallery for Serenity South -- Gardens, River-Views, and Refreshing Space

A hallway with wooden flooring leading to a dining area with a table and chairs.
A living room with a fireplace, a ceiling fan, a television, and a large window.
Terrace/patio
Fridge, microwave, oven, stovetop
Interior

Reviews

10 out of 10
Exceptional

Entire home

3 bedrooms2 bathroomsSleeps 5149 sq m

Popular amenities

  • Kitchen
  • Outdoor Space
  • Parking available
  • Fireplace

Explore the area

View in a map
Cape Girardeau, MO

Room options

About the area

Cape Girardeau

On river.With a stay at this Cape Girardeau vacation home, you'll be within a 5-minute walk of Shawnee National Forest and Mississippi River. EDen Spa & Salon and Riverfront Park are also within half a mile (1 km).
View more Vacation homes in Cape GirardeauOpens in a new window

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 12 min drive

Restaurants

  • ‪Sand's Pancake House - ‬11 min walk
  • ‪Port Cape Girardeau - ‬7 min walk
  • ‪Hotshots Sports Bar & Grill - ‬5 min walk
  • ‪The Library - ‬3 min walk
  • ‪Greens Garden Urban Market + Kitchen - ‬5 min walk

About this property

Entire place

You'll have the entire home to yourself and will only share it with other guests in your party.

Serenity South -- Gardens, River-Views, and Refreshing Space

Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.

Similar properties

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center
Cape Girardeau
  • Pool
  • Hot tub
  • Breakfast included
  • Pet friendly
4.8 out of 5, Exceptional, 1,015 reviews
The price is CA $142
CA $160 total
includes taxes & fees
Jul 26 - Jul 27
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Internet

  • Available in the house: WiFi

Parking and transportation

  • Car not required
  • Parking on site

Kitchen

  • Coffee grinder
  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Ice maker
  • Microwave
  • Oven
  • Paper towels
  • Refrigerator
  • Spices
  • Stovetop
  • Toaster

Bedrooms

  • 3 bedrooms
  • Bedsheets provided

Bathroom

  • 1.5 bathrooms
  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Living spaces

  • Fireplace
  • Separate dining area

Entertainment

  • Books
  • DVD player
  • Games
  • TV

Outdoor areas

  • Balcony
  • Garden
  • Outdoor furniture

Laundry

  • Laundromat nearby

Comfort

  • Air conditioning
  • Heating

Pets

  • No pets allowed

Suitability/Accessibility

  • Smoking not allowed

Services and conveniences

  • Iron/ironing board

Location highlights

  • Near a health/beauty spa
  • Near a hospital
  • Near an outlet shopping mall
  • On a river

Things to do

  • Basketball nearby
  • Casino nearby
  • Cycling nearby
  • Fishing nearby
  • Golfing nearby
  • Hiking/biking trails nearby
  • Horseback riding nearby
  • Motor boating nearby
  • Swimming nearby
  • Wildlife walks nearby
  • Winery tours nearby

Safety features

  • Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
  • Smoke detector (host has indicated there is a smoke detector on the property)
  • Deadbolt lock

General

  • Garden
  • Unit size: 1,600 square feet

Policies

Check-in

Check-in time starts at 4:00 PM
Minimum check-in age: 18

Check-out

Check-out before 11:00 AM

Special check-in instructions

You will receive an email from the host with check-in and check-out instructions
Information provided by the property may be translated using automated translation tools

Rules

Back yard is shared with the other side of the duplex. Please respect their use of the common space.

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Note from host: Excellent fenced back yard.

Events

Events allowed: family gatherings, birthday parties, weddings
Parties or events must okayed before arrival.

Smoking

Smoking is not permitted

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Parties and events (including family gatherings, birthday parties and weddings) are allowed on site; maximum attendees: 50
Note from host: Parties or events must okayed before arrival.
Host has indicated there is a carbon monoxide detector on the property
Host has indicated there is a smoke detector on the property
Safety features at this property include a deadbolt lock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. Parties and events (including family gatherings, birthday parties and weddings) are allowed on site. Maximum attendees: 50. Note from host: Parties or events must okayed before arrival. For guests' safety, the property includes a carbon monoxide detector, a smoke detector, and a deadbolt lock in each accommodation.

Frequently asked questions

How close is Serenity South -- Gardens, River-Views, and Refreshing Space to the airport?

This vacation home is 7.4 mi (12-min drive) away from the Cape Girardeau, MO (CGI-Cape Girardeau Municipal) airport, the closest popular airport to the property.

How much does it cost to stay at Serenity South -- Gardens, River-Views, and Refreshing Space?

As of Jul 11, 2026, prices found for a 1-night stay for 2 adults at Serenity South -- Gardens, River-Views, and Refreshing Space on Jul 24, 2026 start from CA $212, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Does Serenity South -- Gardens, River-Views, and Refreshing Space have an airport shuttle?

Airport shuttle services are not available at this vacation home.

Does Serenity South -- Gardens, River-Views, and Refreshing Space offer free breakfast?

This vacation home does not offer free breakfast.

Is there a casino at Serenity South -- Gardens, River-Views, and Refreshing Space?

No, there is no casino at this vacation home, but Century Casino & Hotel Cape Girardeau (2-min drive) is nearby.

What time is check-in at Serenity South -- Gardens, River-Views, and Refreshing Space?

Check-in begins at 4:00 PM.

Is there free parking at Serenity South -- Gardens, River-Views, and Refreshing Space?

Free parking is not available at this vacation home.

Does Serenity South -- Gardens, River-Views, and Refreshing Space have a pool?

This vacation home does not have a pool.

Does Serenity South -- Gardens, River-Views, and Refreshing Space have a spa?

There are no spa services available at this vacation home.

How close is Serenity South -- Gardens, River-Views, and Refreshing Space to downtown Cape Girardeau?

This vacation home is 0.4 mi away from Cape Girardeau.

Serenity South -- Gardens, River-Views, and Refreshing Space Reviews

Reviews

10

Exceptional

Rating 10 - Excellent. 154 out of 159 reviews
Rating 8 - Good. 5 out of 159 reviews
Rating 6 - Okay. 0 out of 159 reviews
Rating 4 - Poor. 0 out of 159 reviews
Rating 2 - Terrible. 0 out of 159 reviews

10/10

Cleanliness

10/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Marcie R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Nice location to river front and downtown. Very lovely place.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Alison C.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Wonderful location! WonderfulStay
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Vicki R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
It's a great location, great space, great price. And, the muffins are the best!
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Tracy H.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Such a great place and location
Stayed 2 nights in Jul 2025
Verified

10/10 Excellent

John M.

Liked: Cleanliness, check-in, communication, location, listing accuracy
This is a beautiful, well-maintained historic home in a neat part of town -- walking distance to lots of attractions. The hospitality was off the charts. Every detail was thought out. Bed was comfortable, AC worked great, and wonderful spaces (dining room, living room, porch) to hang out in!
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Vicki R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Beautiful house. Great stay. Would definitely stay again!
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Sandy M.

Liked: Cleanliness, check-in, communication, location, listing accuracy
We were visiting our daughter who attends SEMO, so the location was perfect.
Stayed 3 nights in Sep 2025
Verified

10/10 Excellent

Shelley L.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Good stay.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Jodie F.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Enjoyed everything! Great location!
Stayed 4 nights in Jul 2025
Verified

8/10 Good

Tamy R.

Liked: Cleanliness, check-in, communication, listing accuracy
Host was fantastic. House is just like the pictures.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

John

Liked: Cleanliness, property conditions & facilities, communication
Great place.
Stayed 1 night in Dec 2023
Verified

10/10 Excellent

Isaac S.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Home was very tidy, kitchen was spacious, and bedrooms comfortable.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Tim B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great stay

Beautiful home, great location, well equipped kitchen.
Stayed 5 nights in Oct 2022
Verified

10/10 Excellent

Michael R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Nice property near downtown in the river. This was the perfect location for our 50th high school reunion.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Deborah K.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Charming house within walking distance to downtown restaurants and bars. Host is wonderful! Great communication.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Penny F.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Beautiful getaway!

The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area.
Stayed 2 nights in Mar 2025
Verified

10/10 Excellent

Bradley T.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Peaceful place

Very nice and beautiful place super nice people
Stayed 2 nights in Jun 2024
Verified

10/10 Excellent

Danita D.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Historic charm

We loved staying at this house for SEMO family weekend! It was super clean and had everything we needed and more 😊 we will definitely try to stay here again!
Stayed 1 night in Sep 2023
Verified

10/10 Excellent

Terry M.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great family getaway

Everything was perfect. From check in to check out. Great neighborhood and location.
Stayed 1 night in Apr 2024
Verified

10/10 Excellent

Candice L.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Family Graduation

The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!
Stayed 1 night in May 2024
Verified

8/10 Good

Michael W.

Liked: Cleanliness, check-in, communication
All was good except for the strange fact of 3 rentals at the same place and the older couple in the backyard was a little off putting.
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Nolan R.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Wonderful all around!

Great location and property! Stayed with several friends and it’s offered lots of space for everyone. Very close to many downtown attractions! Would definitely stay again!
Stayed 2 nights in Oct 2019
Verified

10/10 Excellent

Sam E.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Downtown home with great character

My son and two brothers stayed a night in this lovely home. I travel to Cape frequently to visit my son and will definitely stay here again.
Stayed 1 night in Apr 2025
Verified

10/10 Excellent

Cheryl R.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Repeat guest

Great home away from home for our visits to Cape.
Stayed 3 nights in Aug 2023
Verified

10/10 Excellent

Tim B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Homecoming

As always, a fantastic place to stay.
Stayed 2 nights in Oct 2023