Entire home
Sanford Hub | Spacious 4BR Across from Sanford
Vacation home near Denny Sanford Premier Center in Sioux Falls
Choose dates to view prices
Photo gallery for Sanford Hub | Spacious 4BR Across from Sanford





Entire home
Popular amenities
- Kitchen
- Washer
- Dryer
- Free WiFi
- Air conditioning
- Parking available
Explore the area
Sioux Falls, SD
- Sanford USD Medical CenterPlace, Sanford USD Medical Center1 min walk
- University of Sioux FallsPlace, University of Sioux Falls5 min walk
- Augustana CollegePlace, Augustana College8 min walk
- Sioux Falls, SD (FSD-Sioux Falls Regional)Airport, Sioux Falls, SD (FSD-Sioux Falls Regional)8 min drive
Room options
About the area
Sioux Falls
In Sioux Falls .Your stay at this Sioux Falls vacation home places you within a 10-minute walk of Sanford USD Medical Center and University of Sioux Falls. Sioux Empire Medical Museum and Augustana College are also within half a mile (1 km).
What's nearby
- Sanford USD Medical Center - 1 min walk - 0.1 km
- University of Sioux Falls - 5 min walk - 0.5 km
- Augustana College - 8 min walk - 0.7 km
- Great Plains Zoo - 19 min walk - 1.7 km
- Washington Pavilion of Arts and Science - 3 min drive - 2.4 km
Getting around
- Sioux Falls Regional Airport (FSD) - 12 min drive
Restaurants
- Fryn' Pan - 20 min walk
- Taco John's - 2 min drive
- Giliberto's Mexican Taco Shop - 2 min drive
- The Dive - 8 min walk
- Taco Bell - 2 min drive
About this property
Entire place
You'll have the entire home to yourself and will only share it with other guests in your party.
Sanford Hub | Spacious 4BR Across from Sanford
Your spacious, beautifully updated home-base directly across the street from Sanford Medical Center & Sanford Children’s Hospital.
Steps to Sanford – walk from the front door to either main entrance in under 2 minutes.
Room for everyone – 4 bedrooms: 4 comfy queen beds in three rooms plus a day-bed with roll-out trundle (sleeps 10) in the last bedroom.
2 refreshed baths stocked with plush towels & toiletries.
White-brick charm – bright interior with painted-brick accents, stylish feature walls & hardwood floors.
Fully equipped kitchen – stainless appliances, quartz-style counters, drip & Keurig coffee, basic pantry staples.
Smart living area – 55` Roku TV, fast Wi-Fi, board games & a mini work nook.
Back-yard oasis – landscaped yard, roomy deck, grill & lights for evening hangs.
Hassle-free parking – attached garage + extra off-street spots in the driveway.
Self check-in via smart keypad, washer/dryer on site, central heat & AC.
Discounts for 7-night & 30-night stays – perfect for traveling nurses, patients’ families, university visitors, or extended work trips.
The Space
Built in 1947 and recently renovated from top to bottom, Sanford Hub blends mid-century bones with modern comfort. The main level flows from a sun-lit living room into the cheery kitchen. Down the hall you’ll find a queen bedroom a day-bed/trundle and trundle bed plus a full bath. Downstairs, a bedroom holds two queen beds and another bedroom down the hallway has another queen. The finished lower level also has a ¾ bath and laundry.
Guest Access
Guests have exclusive use of the entire home, garage, back deck, and fenced yard. Keypad code is sent the morning of arrival for seamless 24-hour check-in.
Neighborhood
Medical: Literally across 22nd Street from Sanford & Sanford Children’s.
Universities: <1 mi to Augustana University & University of Sioux Falls.
Downtown: 5-min drive to Falls Park, cafés, boutiques, and nightlife.
Parks & Zoo: Great Plains Zoo & Terrace Park are just minutes away.
Getting Around
Bring a car for maximum flexibility, but rideshares reach downtown in ~5 minutes and the hospital in seconds. Bike lanes and wide sidewalks make the neighborhood very walkable.
House Rules
No parties, events, or indoor smoking.
Steps to Sanford – walk from the front door to either main entrance in under 2 minutes.
Room for everyone – 4 bedrooms: 4 comfy queen beds in three rooms plus a day-bed with roll-out trundle (sleeps 10) in the last bedroom.
2 refreshed baths stocked with plush towels & toiletries.
White-brick charm – bright interior with painted-brick accents, stylish feature walls & hardwood floors.
Fully equipped kitchen – stainless appliances, quartz-style counters, drip & Keurig coffee, basic pantry staples.
Smart living area – 55` Roku TV, fast Wi-Fi, board games & a mini work nook.
Back-yard oasis – landscaped yard, roomy deck, grill & lights for evening hangs.
Hassle-free parking – attached garage + extra off-street spots in the driveway.
Self check-in via smart keypad, washer/dryer on site, central heat & AC.
Discounts for 7-night & 30-night stays – perfect for traveling nurses, patients’ families, university visitors, or extended work trips.
The Space
Built in 1947 and recently renovated from top to bottom, Sanford Hub blends mid-century bones with modern comfort. The main level flows from a sun-lit living room into the cheery kitchen. Down the hall you’ll find a queen bedroom a day-bed/trundle and trundle bed plus a full bath. Downstairs, a bedroom holds two queen beds and another bedroom down the hallway has another queen. The finished lower level also has a ¾ bath and laundry.
Guest Access
Guests have exclusive use of the entire home, garage, back deck, and fenced yard. Keypad code is sent the morning of arrival for seamless 24-hour check-in.
Neighborhood
Medical: Literally across 22nd Street from Sanford & Sanford Children’s.
Universities: <1 mi to Augustana University & University of Sioux Falls.
Downtown: 5-min drive to Falls Park, cafés, boutiques, and nightlife.
Parks & Zoo: Great Plains Zoo & Terrace Park are just minutes away.
Getting Around
Bring a car for maximum flexibility, but rideshares reach downtown in ~5 minutes and the hospital in seconds. Bike lanes and wide sidewalks make the neighborhood very walkable.
House Rules
No parties, events, or indoor smoking.
Similar properties

Charming University Cottage, Prime Location
Charming University Cottage, Prime Location
University Heights
- Kitchen
- Washer
- Dryer
- Pet friendly
4.8 out of 5, Exceptional, 5 reviews
4.8
Exceptional
5 reviews

Blue House Retreat 2
Blue House Retreat 2
Sioux Falls
- Kitchen
- Washer
- Dryer
- Air conditioning
5.0 out of 5, Exceptional, 11 reviews
5
Exceptional
11 reviews

New Cottage Steps from Sanford
New Cottage Steps from Sanford
Pettigrew Heights
- Kitchen
- Washer
- Air conditioning
- Parking available
4.8 out of 5, Exceptional, 4 reviews
4.8
Exceptional
4 reviews
The price is CA $97
CA $97
CA $254 total
includes taxes & fees
Jan 4 - Jan 5

The Cozy Corner - A 2BR Retreat
The Cozy Corner - A 2BR Retreat
Pettigrew Heights
- Kitchen
- Washer
- Dryer
- Air conditioning
4.4 out of 5, Excellent, 6 reviews
4.4
Excellent
6 reviews

Relaxing 2 Bed 2 Bath with Garage!
Relaxing 2 Bed 2 Bath with Garage!
Sioux Falls
- Kitchen
- Washer
- Dryer
- Pet friendly
5.0 out of 5, Exceptional, 80 reviews
5
Exceptional
80 reviews

The Sophisticated Apartment- 2 Bedroom Apartment Unit in Downtown Sioux Falls
The Sophisticated Apartment- 2 Bedroom Apartment Unit in Downtown Sioux Falls
Cathedral
- Kitchen
- Washer
- Dryer
- Pet friendly
4.6 out of 5, Wonderful, 76 reviews
4.6
Wonderful
76 reviews
The price is CA $101
CA $101
CA $214 total
includes taxes & fees
Jan 4 - Jan 5

Historic Victorian Inn North Loft
Historic Victorian Inn North Loft
Cathedral
- Free WiFi
- Air conditioning
- Tennis court
- Game room
5.0 out of 5, Exceptional, 1 review
5
Exceptional
1 review
The price is CA $153
CA $153
CA $218 total
includes taxes & fees
Jan 4 - Jan 5

Historic Twin Tudors Inn
Historic Twin Tudors Inn
Sioux Falls
- Parking included
- Free WiFi
- Air conditioning
- Tennis court
4.4 out of 5, Excellent, 3 reviews
4.4
Excellent
3 reviews
The price is CA $369
CA $369
CA $419 total
includes taxes & fees
Jan 4 - Jan 5

Historic Victorian Inn
Historic Victorian Inn
Cathedral
- Free airport shuttle
- Parking included
- Free WiFi
- Air conditioning
4.4 out of 5, Excellent, 56 reviews
4.4
Excellent
56 reviews
The price is CA $187
CA $187
CA $228 total
includes taxes & fees
Jan 22 - Jan 23

Holiday Inn Express and Suites Sioux Falls SW by IHG
Holiday Inn Express and Suites Sioux Falls SW by IHG
South Sioux Falls
- Pool
- Hot tub
- Breakfast included
- Kids pool
4.4 out of 5, Excellent, 1,003 reviews
4.4
Excellent
1,003 reviews
The price is CA $147
CA $147
CA $164 total
includes taxes & fees
Feb 1 - Feb 2
Property amenities
Internet
- Available in the house: Free WiFi
Parking and transportation
- Onsite parking options include a garage
Kitchen
- Coffee/tea maker
- Cookware, dishware, and utensils
- Dishwasher
- Kitchen island
- Microwave
- Oven
- Refrigerator
- Stovetop
- Toaster
Dining
- Dining table
Bedrooms
- Bedsheets provided
Bathroom
- 2 bathrooms
- Towels provided
Living spaces
- Dining table
- Separate dining area
Entertainment
- Smart TV
Outdoor areas
- Barbecue grill
- Fenced yard
Laundry
- Washing machine
Work spaces
- Desk
- Desk chair
Comfort
- Air conditioning
- Heating
Pets
- No pets allowed
Suitability/Accessibility
- Smoking not allowed
Services and conveniences
- Iron/ironing board
Location highlights
- Near a hospital
Safety features
- Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
- Smoke detector (host has indicated there is a smoke detector on the property)
- First aid kit
- Fire extinguisher
Policies
Check-in
Check-in time starts at 4:00 PM
Minimum check-in age: 18
Check-out
Check-out before 10:00 AM
Special check-in instructions
You will receive an email from the host with check-in and check-out instructions
Information provided by the property may be translated using automated translation tools
Pets
- No pets allowed
Children and extra beds
- Children are welcome.
Events
No events allowed
Smoking
Smoking is not permitted
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Onsite parties or group events are strictly prohibited
Host has indicated there is a carbon monoxide detector on the property
Host has indicated there is a smoke detector on the property
Safety features at this property include a fire extinguisher and a first aid kit
This property has outdoor spaces, such as balconies, patios, terraces which may not be suitable for children; if you have concerns, we recommend contacting the property prior to your arrival to confirm they can accommodate you in a suitable room
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
A cash deposit, credit card, or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
- This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession. This property has outdoor spaces, such as balconies, patios, terraces which may not be suitable for children. If you have concerns, we recommend contacting the property prior to your arrival to confirm they can accommodate you in a suitable room. Onsite parties or group events are strictly prohibited. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, and a first aid kit in each accommodation.
Property is also known as
405157